CHiP Network Congenital Heart Journal Watch – November 2019-Archive
Pediatric Cardiology Featured Articles
Pediatric Cardiology Reviews of September 2019 Manuscripts
Pediatric Cardiology Reviews of September 2019 Manuscripts
2-Year Outcomes After Complete or Staged Procedure for Tetralogy of Fallot in Neonates.
Savla JJ, Faerber JA, Huang YV, Zaoutis T, Goldmuntz E, Kawut SM, Mercer-Rosa L.
J Am Coll Cardiol. 2019 Sep 24;74(12):1570-1579. doi: 10.1016/j.jacc.2019.05.057.
PMID: 31537267
Take-Home Points:
- Complete repair has a higher mortality than a staged approach in neonates with tetralogy.
- Postoperative cardiac complications are the most likely mediator for this relationship.
Commentary from Dr. Jared Hershenson (Greater Washington DC), section editor of Pediatric Cardiology Journal Watch: Symptomatic/cyanotic infants with TOF require neonatal intervention. There has been debate as to the better strategy: palliation with a shunt or complete repair. Both have advantages and disadvantages. Shunt palliation will prolong cyanosis and require a 2nd surgery. However, complete repair is a more complex procedure with a longer hospital course and less patients would be able to have a valve-sparing repair, which likely has much better long term consequences. It is known that neonatal repair has a higher morbidity and mortality than later complete repair, but it has not yet been clear which approach may result in the best outcomes in the neonatal population.
This was a retrospective cohort study using the Pediatric Health Information System (PHIS) database between 2004-2015. Primary outcome was death during the 2 year follow up after initial procedure. Somewhat complex statistics were necessary to control for patient and hospital based characteristics, as both could influence the choice of surgical approach. An inverse probability weighted Cox model was used to estimate the effect of the initial procedure on late mortality and a logistic regression was used to analyze mortality within the first hospitalization. To address unmeasured confounding variables and their relative strength, E values were calculated for the estimated hazard and odds ratios.
2363 patients were studied; 1032 had a complete repair and 1331 were staged. Table 1 showed good balance in the weighted sample, with no demographic or patient characteristics being significantly different (all < 10%). Surgeries were performed at 45 hospitals; 24% performed greater than ⅔ complete repairs, 33% performed greater than ⅔ staged repairs, and 42% had equal proportions. Median length of initial hospital stay was 16 days for the complete repair and 15 days for the staged repair. There were 239 deaths, 92 in the complete and 147 in the staged groups. Figure 1 shows the breakdown of each cohort. Complete repair had a greater risk for mortality within the 2 year follow up (HR 1.51) and is shown graphically below. There was no difference within the first week, but from day 7-30 (early), the complete group had an increased risk of mortality (HR 2.29). E-value calculations indicated that only the presence of very strong unmeasured confounders could explain the association of type of repair and survival. See Table 2. At least one in-hospital cardiac complication was observed in 36.1% of the complete group and 15.4% of the staged group. This was shown to be the primary mediator between surgical approach and mortality, with 87% of the total effect attributable to early mortality and 80% to late mortality. Non-cardiac complications did not mediate the treatment-mortality relationship. However, subgroup analysis did not show a difference in mortality for patients who received a BT shunt versus complete repairs, nor were there differences in those that received an RV to PA conduit within the complete repair group. The authors write that the trend was similar for benefit of BT shunt over complete repair, but the study was possibly underpowered to detect a significant relationship.
As an accompanying editorial suggests, given the limitation of an administrative dataset, the most likely influence of this study will be on those considered to be higher risk. If there is a way to identify those that are more likely to have a cardiac complication, or a way to prevent that complication from occurring, then complete repair risk may be mitigated. Additionally, of those patients in the staged group that did not receive a BT shunt, was it improved catheter based therapy such as RVOT stenting or PDA stenting that led to the improved mortality? Overall, it does seem that a less-invasive initial approach should be favored, especially in the highest risk patients, and decision-making should be individualized to achieve the best possible results. A risk-stratification model may be the next logical step to help determine who may benefit the most from a given therapy.
Pharmacologic stress cardiovascular magnetic resonance in the pediatric population: A review of the literature, proposed protocol, and two examples in patients with Kawasaki disease.
Fares M, Critser PJ, Arruda MJ, Wilhelm CM, Rattan MS, Lang SM, Alsaied T.
Congenit Heart Dis. 2019 Sep 9. doi: 10.1111/chd.12840. [Epub ahead of print] Review.
PMID: 31498562
Take-Home Points:
- Pharmacologic stress cardiovascular MRI (PSCMR) is an underused but potentially very helpful modality in assessing certain types of pediatric CHD, especially those with coronary abnormalities or coronary reimplantation.
- Further focused research as well as cost-analysis may be useful, but integrating this with a larger stress perfusion testing center may be most effective.
Commentary from Dr. Jared Hershenson (Greater Washington DC), section editor of Pediatric Cardiology Journal Watch: A large trial recently published in JACC on MRI stress perfusion in adults with coronary artery disease received a lot of attention due to the high sensitivity and cost-effectiveness of what is a clearly underused and under-available modality. This was a review article on its use in the pediatric/adult congenital population along with proposed protocols. Exercise stress testing is of course not feasible for all patients, but the sensitivity and specificity may be low, especially when trying to assess perfusion of the right ventricle. This is also a known limitation of nuclear testing. Often times, pediatric cardiologists need to make decisions based on echo findings, standard stress testing, or sometimes resort to an invasive cardiac catheterization, but which still do not always provide the prognostic information necessary to decide whether surgery or other management needs to occur.
Table 1 lists high risk cohorts who could theoretically benefit from PSCMR which can be categorized as surgical coronary reimplantation, anomalous coronary artery (AAOCA), acquired disease (such as Kawasaki disease (KD)), or systemic right ventricle. Inotropic agents (dobutamine) and coronary vasodilator agents can be used to mimic physical exercise. Dobutamine may be better utilized when there is concern for dynamic obstruction such as in AAOCA or myocardial bridging. A newer vasodilating agent, Regandenoson, has a better side effect profile and only requires a single bolus instead of a continuous infusion as needed in older agents (adenosine/dipyridamole). The authors list the few, relatively small, studies done using PSCMR, and highlight the fact that there is data to suggest higher sensitivity and specificity, along with the advantages of no radiation exposure and not being limited by acoustic windows (as stress echo may be). They also provide a suggested protocol along with dosage when using dobutamine, adenosine, and regadenoson and provide a conceptual framework for imaging (Figure 1). Finally, they discuss 2 case reports of patients with KD and the clear utility of PSCMR. The first case was a patient with a history of giant aneurysms that had mostly resolved and with a normal treadmill stress test. PSCMR showed perfusion defects, and the patient ultimately underwent cutting balloon dilation. The 2nd case was a young patient (4 years old), too young to undergo standard stress testing, with giant aneurysms and perfusion defects. A cath showed near occlusion of the LAD and he underwent CABG.
Hopefully, there will be further published studies looking at PSCMR in pediatric patients, as this is a modality that can be very helpful in certain subgroups for which current testing is limited.
Necrotizing Enterocolitis and Associated Mortality in Neonates With Congenital Heart Disease: A Multi-Institutional Study.
Spinner JA, Morris SA, Nandi D, Costarino AT, Marino BS, Rossano JW, Shamszad P.
Pediatr Crit Care Med. 2019 Sep 20. doi: 10.1097/PCC.0000000000002133. [Epub ahead of print]
PMID: 31568264
Select item 31546957
Take-Home Points:
- The prevalence of NEC in neonates with congenital heart disease is 3.7 %.
- Hypoplastic Left Heart Syndrome and TA were the two cardiac lesions associated with the highest frequency of NEC. The odds of developing NEC were 2.7 and 2.6 times when compared to the lesion with the lowest incidence of NEC, that is Transposition of great arteries.
- Adjusted risk factors associated with the development of NEC included prematurity, male sex, AA race, GI abnormality, and additional birth defects.
- The overall hospital mortality of neonates with CHD and NEC was significantly higher than compared to neonates with CHD and no NEC.
- NEC was also associated with increased total hospital charges, longer ICU LOS and hospital LOS when compared to those without NEC and the association remained significant when analyzed by the individual cardiac defect.
- No association was found with a 30-day readmission rate.
Commentary from Dr. Venugopal Amula (Salt Lake City, UT), section editor of Pediatric Cardiology Journal Watch: This is a retrospective multi-institutional study describing the prevalence and mortality of necrotizing enterocolitis (NEC) in neonates with congenital heart disease. The Pediatric Health Information System database was queried for all index hospitalizations involving neonates with CHD between 2004 to 2015 and the primary outcome was the presence of NEC during the index hospitalization. Secondary outcomes studied included in-hospital mortality, hospital LOS, ICU LOS, hospital charges and 30-day readmission. Multivariable analysis for the presence of NEC and in-hospital mortality were performed for each heart defect category utilizing generalized estimating equations to adjust for hospital clustering. The heart defect categories included Single ventricle, Tricuspid atresia (TA), Truncus arteriosus, Transposition of great arteries, Tetralogy of Fallot and isolated arch obstruction. Variables included in the multivariable model for the presence of NEC were prematurity, African American race, male sex, additional birth defect or GI anomaly.
2019 updated consensus statement on the diagnosis and treatment of pediatric pulmonary hypertension: The European Pediatric Pulmonary Vascular Disease Network (EPPVDN), endorsed by AEPC, ESPR and ISHLT.
Hansmann G, Koestenberger M, Alastalo TP, Apitz C, Austin ED, Bonnet D, Budts W, D’Alto M, Gatzoulis MA, Hasan BS, Kozlik-Feldmann R, Kumar RK, Lammers AE, Latus H, Michel-Behnke I, Miera O, Morrell NW, Pieles G, Quandt D, Sallmon H, Schranz D, Tran-Lundmark K, Tulloh RMR, Warnecke G, Wåhlander H, Weber SC, Zartner P.
J Heart Lung Transplant. 2019 Sep;38(9):879-901. doi: 10.1016/j.healun.2019.06.022. Epub 2019 Jun 21.
PMID: 31495407
Select item 31324444
Take-Home Points:
- Based on the World Symposium of Pulmonary Hypertension WSPH ( Nice, 2018) PH is now defined as mean Pulmonary Artery Pressure (mPAP) > 20mm in children > 3 months of age at sea level. The limit was decreased from 24 to 20mm hg based on adult studies where even mild elevation of mPAP between 20-24mm Hg was found to be independent predictor of poor survival.
- Children with suspected PH should be evaluated, treated and monitored in specialized pediatric centers. The initial evaluation should include a comprehensive medical history, physical examination, assignment to the functional class, assessment of cardiac function by ECG, Echocardiogram. Further testing and advance imaging is guided by the key findings in the history and include but are not limited to cardiac catheterization, HR-Chest CT with angiography, V/Q scan, Sleep study, Blood gas analysis, Lung function test, etc.
- Some determinants of higher risk in pediatric PH include clinical evidence of RV failure, progressive symptoms, presence of syncope, growth failure, severely elevated Serum NT-proBNP (> 1200 pg/ml (>1 yr. old).
- Transthoracic Echocardiogram (TTE) cannot establish a definite diagnosis of PH or determine WHO PH group. PH diagnosed by TTE should be confirmed by catheterization before initiation of targeted PH therapy except in infants with PPHN, BPD and those with high risk. We should rely on a multiparametric approach other than single parameters. Echo or CMR variables that are determinants of high risk include evidence of severe RA/RV enlargement, RV systolic dysfunction, RV/LV end systolic ratio of >1.5, TAPSE ¯¯ (Z-score , -3). Systolic/Diastolic ratio > 1.4 (TR jet ), Pulmonary Artery Acceleration Time PAAT < 70ms and Pericardial effusion.
Cardiac catheterization is indicated in all pediatric patients with PH to confirm a diagnosis and determine severity, especially when considering pharmacotherapy except in infants and Low body weight or those presenting critically ill where it can be omitted until more stable. The cardiac catheterization should include Acute Vasoreactivity testing. In children with IPAH/HPAH, the hemodynamic change that defines a positive response to AVT in PH without CV shunt is > 20% fall in mPAP and PVR/SVR ratio without a decrease in CI. Invasive hemodynamics that portend high risk include Cardiac Index < 2.5. mRAP> 15, mPAP/mSAP> 0.75, PVRi> 15 Wu-m
- In centers equipped to perform advanced pediatric cardiac magnetic resonance imaging, CMR without anesthesia /sedation is recommended as a part of diagnostic evaluation and follow up to assess changes in ventricular function and chamber dimensions.
- Several Pulmonary Arterial Hypertension (PAH) associated genes have been identified and genetic testing can allow the definition of PAH etiology, estimation of prognosis and identification of families at risk. Hence genetic counseling by trained personnel before genetic testing is recommended for families with children diagnosed with Idiopathic PAH or Heritable PAH. Children who are asymptomatic PAH mutation carriers, asymptomatic first-degree relatives of patients with HPAH without an associated gene mutation should be screened by serial echocardiograms every 1-3 yrs. for the presence of elevated RV pressure and undergo additional diagnostic evaluation if clinically indicated.
- In patients with PAH associated with congenital heart disease a complete diagnostic workup should be performed to determine whether PAH is associated with or causally related to concomitant CHD. Children with simple shunt defects beyond the typical timing of surgery (> 6 months old ) and with severe cyanosis should undergo comprehensive right and left heart catheterization before any intervention or surgery. Standard management is adopted for PVR1< 6 Wu-m2 and PVR/SVR < 0.3. For patients in gray zone PVRi 6-8 Wu -m2 – a treat and repair approach is reasonable using PAH targeted pharmacotherapy with 1-2 medications. A shunt defect must not be closed in when PVRi > 8 Wu- m2 in children.
- The term and preterm newborn infant with PPHN should receive oxygen, ventilatory support, surfactant with a goal preductal sat of 91-95 %. Inhaled Nitric Oxide is indicated to improve oxygenation and to reduce the need for ECMO if PaO2 < 100 on 100% oxygen or OI index > 25. In the presence of right heart failure preterm and term infants with PPHN should receive PGE infusion to maintain ductal patency in the absence of post tricuspid unrestrictive shunt.
- In the pediatric ICU, oxygen is administered when the SaO2 < 95% in children with PH and normal anatomy. iNO may be considered for postoperative PH treatment in mechanically ventilated patients to improve oxygenation and reduce PHT crises. Concomitant sildenafil should be administered to prevent rebound PH while weaning iNO. Inhaled iloprost can be as effective as iNO in children with postoperative PH.
- The diagnosis and management of PH in middle and low-income regions should be done with specialized centers and endemic diseases should be considered in etiology. Schistosomiasis, Rheumatic heart disease, HIV infection, high altitude, chronic hepatitis, etc. should be considered. Treatment should be based on individual case assessment and PAH targeted medications may help especially when pursued at centers specialized in PH.
- Treatment of PH should be under expert guidance. Supportive therapy with oxygen, Diuretic therapy, anticoagulation should be based on a specific type of PH, CCB should be considered in those patients who are acutely reactive to iNO with or without oxygen. They should be avoided in AVT nonresponders and children with right heart failure regardless of AVT response.
Commentary from Dr. Venugopal Amula (Salt Lake City, UT), section editor of Pediatric Cardiology Journal Watch: To provide a specific, comprehensive, detailed and practical framework for the clinical care of children and young adults with Pulmonary Hypertension, the European Pediatric Pulmonary Vascular Disease Network constituted an executive writing group. The executive writing group members conducted a thorough scientific review and generated tables with graded recommendations based on the European Society of Cardiology/ American Heart Association definitions. They included studies with pediatric data only, adult studies that included> 10% of children or studies that enrolled adults with CHD. Although the majority of recommendations on pediatric PH are based on the level of evidence B or C, much effort has been made to obtain pediatric data from registries and clinical studies. A summary of such recommendations is provided below.
Updated Clinical Classification of Pulmonary Hypertension, WSPH, Nice, 2018
Diagnostic algorithm for a child or young adult with suspected pulmonary hypertension
Algorithm for management of patients with CHD associated with PAH/Pulmonary Hypertensive Vascular Disease and congenital shunt lesions.
Treatment algorithm for Pediatric PAH
Pediatric cardiology Sept 2019
Baglivo M, Dassati S, Krasi G, Fanelli F, Kurti D, Bonelli A, Arabia G, Fabbicatore D, Muneretto C, Bertelli M.
Acta Biomed. 2019 Sep 30;90(10-S):53-57. doi: 10.23750/abm.v90i10-S.8760.
PMID: 31577255
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Kühnisch J, Herbst C, Al-Wakeel-Marquard N, Dartsch J, Holtgrewe M, Baban A, Mearini G, Hardt J, Kolokotronis K, Gerull B, Carrier L, Beule D, Schubert S, Messroghli D, Degener F, Berger F, Klaassen S.
Clin Genet. 2019 Sep 30. doi: 10.1111/cge.13645. [Epub ahead of print]
PMID: 31568572
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Alanzi T, Alhashem A, Dagriri K, Alzahrani F, Alkuraya FS.
Eur J Hum Genet. 2019 Sep 30. doi: 10.1038/s41431-019-0524-0. [Epub ahead of print]
PMID: 31570783
Select item 31569967
Dahlawi N, Milnes LJ, Swallow V.
J Child Health Care. 2019 Sep 30:1367493519878550. doi: 10.1177/1367493519878550. [Epub ahead of print]
PMID: 31569967
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Mastromoro G, Capalbo A, Guido CA, Torres B, Fabbretti M, Traversa A, Giancotti A, Ventriglia F, Bernardini L, Spalice A, Pizzuti A.
Eur J Med Genet. 2019 Sep 27:103772. doi: 10.1016/j.ejmg.2019.103772. [Epub ahead of print]
PMID: 31568860
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Sallmon H, Moledina S, Albert DC, Beghetti M, Berger RMF, Bonnet D, Bukova M, Koestenberger M, Meinel K, Reinhardt Z, Tulloh RMR, de Wolf D, Hansmann G.
Cardiol Young. 2019 Sep 26:1-5. doi: 10.1017/S104795111900235X. [Epub ahead of print]
PMID: 31554525
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Wang G, Zhou G.
J Card Surg. 2019 Sep 26. doi: 10.1111/jocs.14268. [Epub ahead of print]
PMID: 31557345
Select item 31558080
Naef N, Wehrle F, Rousson V, Latal B.
J Pediatr. 2019 Sep 25. pii: S0022-3476(19)31094-7. doi: 10.1016/j.jpeds.2019.08.036. [Epub ahead of print]
PMID: 31563274
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Van Arsdell GS, Levi DS.
J Am Coll Cardiol. 2019 Sep 24;74(12):1580-1581. doi: 10.1016/j.jacc.2019.06.031. No abstract available.
PMID: 31537268
Select item 31537267
Cognata A, Kataria-Hale J, Griffiths P, Maskatia S, Rios D, O’Donnell A, Roddy DJ, Mehollin-Ray A, Hagan J, Placencia J, Hair AB.
J Pediatr. 2019 Sep 24. pii: S0022-3476(19)30993-X. doi: 10.1016/j.jpeds.2019.08.009. [Epub ahead of print]
PMID: 31561958
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Pruetz JD, Wang SS, Noori S.
Semin Fetal Neonatal Med. 2019 Sep 24:101034. doi: 10.1016/j.siny.2019.101034. [Epub ahead of print] Review.
PMID: 31582282
Select item 31547669
Kalisch-Smith JI, Ved N, Sparrow DB.
Cold Spring Harb Perspect Biol. 2019 Sep 23. pii: a037234. doi: 10.1101/cshperspect.a037234. [Epub ahead of print]
PMID: 31548181
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Tan NY, Attenhofer Jost CH, Polkinghorne MD, Vargas ER, Hodge DO, Dearani JA, Asirvatham SJ, Connolly HM, McLeod CJ.
Congenit Heart Dis. 2019 Sep 23. doi: 10.1111/chd.12841. [Epub ahead of print]
PMID: 31545019
Select item 31545015
DiPaola F, Trout AT, Walther AE, Gupta A, Sheridan R, Campbell KM, Tiao G, Bezerra JA, Bove KE, Patel M, Nathan JD.
Dig Dis Sci. 2019 Sep 23. doi: 10.1007/s10620-019-05834-w. [Epub ahead of print]
PMID: 31549332
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Saitta S, Pirola S, Piatti F, Votta E, Lucherini F, Pluchinotta F, Carminati M, Lombardi M, Geppert C, Cuomo F, Figueroa CA, Xu XY, Redaelli A.
J Biomech. 2019 Sep 20;94:13-21. doi: 10.1016/j.jbiomech.2019.07.004. Epub 2019 Jul 9.
PMID: 31326119
Select item 31539915
Spinner JA, Morris SA, Nandi D, Costarino AT, Marino BS, Rossano JW, Shamszad P.
Pediatr Crit Care Med. 2019 Sep 20. doi: 10.1097/PCC.0000000000002133. [Epub ahead of print]
PMID: 31568264
Select item 31546957
Hudson KM, Belcher SM, Cowley M.
Sci Rep. 2019 Sep 19;9(1):13553. doi: 10.1038/s41598-019-49807-5.
PMID: 31537853 Free PMC Article
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Lahrouchi N, Raju H, Lodder EM, Papatheodorou S, Miles C, Ware JS, Papadakis M, Tadros R, Cole D, Skinner JR, Crawford J, Love DR, Pua CJ, Soh BY, Bhalshankar JD, Govind R, Tfelt-Hansen J, Winkel BG, van der Werf C, Wijeyeratne YD, Mellor G, Till J, Cohen M, Tome-Esteban M, Sharma S, Wilde AAM, Cook SA, Sheppard MN, Bezzina CR, Behr ER.
Eur J Hum Genet. 2019 Sep 18. doi: 10.1038/s41431-019-0500-8. [Epub ahead of print]
PMID: 31534214
Select item 31533991
Gerdes H, Lantos J.
HEC Forum. 2019 Sep 18. doi: 10.1007/s10730-019-09384-6. [Epub ahead of print]
PMID: 31535261
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Xu J, Guthrey C, Dalby S, Tang X, Daily J, Collins RT.
Pediatr Cardiol. 2019 Sep 18. doi: 10.1007/s00246-019-02210-3. [Epub ahead of print]
PMID: 31535184Similar articles
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- Pediatric Hemoptysis without Bronchiectasis or Cardiac Disease: Etiology, Recurrence, and Mortality.
Chiel L, Welsh S, Andren K, Mecklosky J, Alexander PMA, Casey A, Fishman MP.
J Pediatr. 2019 Sep 17. pii: S0022-3476(19)30957-6. doi: 10.1016/j.jpeds.2019.07.049. [Epub ahead of print]
PMID: 31540762
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Hewitson LJ.
BMJ Case Rep. 2019 Sep 16;12(9). pii: e229590. doi: 10.1136/bcr-2019-229590.
PMID: 31527200
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Seed M.
Int J Cardiol. 2019 Sep 15;291:50-51. doi: 10.1016/j.ijcard.2019.05.038. Epub 2019 May 20. No abstract available.
PMID: 31151765
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Culliford-Semmens N, Nicholson R, Tilton E, Stirling J, Sidhu K, Webb R, Wilson N.
Int J Cardiol. 2019 Sep 15;291:112-118. doi: 10.1016/j.ijcard.2019.02.058. Epub 2019 Mar 2.
PMID: 30851993
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Dianatpour S, Khatami M, Heidari MM, Hadadzadeh M.
Appl Biochem Biotechnol. 2019 Sep 13. doi: 10.1007/s12010-019-03125-8. [Epub ahead of print]
PMID: 31515672
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Piché J, Van Vliet PP, Pucéat M, Andelfinger G.
Cell Cycle. 2019 Sep 13:1-21. doi: 10.1080/15384101.2019.1658476. [Epub ahead of print]
PMID: 31516082
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Peer SM, Jonas RA.
Ann Thorac Surg. 2019 Sep 12. pii: S0003-4975(19)31270-6. doi: 10.1016/j.athoracsur.2019.07.045. [Epub ahead of print] No abstract available.
PMID: 31521596
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Zhao Z, Zhan Y, Chen W, Ma X, Sheng W, Huang G.
Genesis. 2019 Sep 12:e23333. doi: 10.1002/dvg.23333. [Epub ahead of print]
PMID: 31513339
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Jonas MC, Ramalho FS, Vicente WVA, Manso PH.
Autops Case Rep. 2019 Sep 11;9(3):e2019118. doi: 10.4322/acr.2019.118. eCollection 2019 Jul-Sep.
PMID: 31583210 Free PMC Article
Ribera I, Ruiz A, Sánchez O, Eixarch E, Antolín E, Gómez-Montes E, Pérez-Cruz M, Cruz-Lemini M, Sanz-Cortés M, Arévalo S, Ferrer Q, Vázquez E, Vega L, Dolader P, Montoliu A, Boix H, Simões RV, Masoller N, Sánchez-de-Toledo J, Comas M, Bartha JM, Galindo A, Martínez JM, Gómez-Roig L, Crispi F, Gómez O, Carreras E, Cabero L, Gratacós E, Llurba E.
BMC Pediatr. 2019 Sep 10;19(1):326. doi: 10.1186/s12887-019-1689-y.
PMID: 31506079 Free PMC Article
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Sierra-Galan LM, François CJ.
Curr Treat Options Cardiovasc Med. 2019 Sep 10;21(10):58. doi: 10.1007/s11936-019-0758-8. Review.
PMID: 31506869
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Clancy T, Jordan B, de Weerth C, Muscara F.
J Clin Psychol Med Settings. 2019 Sep 10. doi: 10.1007/s10880-019-09651-1. [Epub ahead of print] Review.
PMID: 31506852
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Fares M, Critser PJ, Arruda MJ, Wilhelm CM, Rattan MS, Lang SM, Alsaied T.
Congenit Heart Dis. 2019 Sep 9. doi: 10.1111/chd.12840. [Epub ahead of print] Review.
PMID: 31498562
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Steele JM, Komarlu R, Worley S, Alsaied T, Statile C, Erenberg FG.
Congenit Heart Dis. 2019 Sep 6. doi: 10.1111/chd.12829. [Epub ahead of print]
PMID: 31489778
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Kurdi AM, Majeed-Saidan MA, Al Rakaf MS, AlHashem AM, Botto LD, Baaqeel HS, Ammari AN.
BMJ Open. 2019 Sep 5;9(9):e026351. doi: 10.1136/bmjopen-2018-026351.
PMID: 31492776 Free PMC Article
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Ma XJ, Huang GY.
Chin Med J (Engl). 2019 Sep 5;132(17):2105-2108. doi: 10.1097/CM9.0000000000000375.
PMID: 31348032
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Luo X, Li Z.
Echocardiography. 2019 Sep 5. doi: 10.1111/echo.14469. [Epub ahead of print]
PMID: 31487070
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Callahan K, Steinwurtzel R, Brumarie L, Schechter S, Parravicini E.
J Perinatol. 2019 Sep 5. doi: 10.1038/s41372-019-0490-y. [Epub ahead of print]
PMID: 31488903
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Kylat RI.
Children (Basel). 2019 Sep 4;6(9). pii: E98. doi: 10.3390/children6090098.
PMID: 31487969 Free Article
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Pinna V, Daniele P, Calcagni G, Mariniello L, Criscione R, Giardina C, Lepri FR, Hozhabri H, Alberico A, Cavone S, Morella AT, Mandile R, Annunziata F, Di Giosaffatte N, D’Asdia MC, Versacci P, Capolino R, Strisciuglio P, Giustini S, Melis D, Digilio MC, Tartaglia M, Marino B, De Luca A.
Genes (Basel). 2019 Sep 4;10(9). pii: E675. doi: 10.3390/genes10090675.
PMID: 31487937 Free Article
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Wong AK, Channick RN.
Drug Healthc Patient Saf. 2019 Sep 3;11:71-85. doi: 10.2147/DHPS.S173050. eCollection 2019.
PMID: 31564989 Free PMC Article
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Constantine A, Barradas-Pires A, Dimopoulos K.
Eur J Prev Cardiol. 2019 Sep 3:2047487319874146. doi: 10.1177/2047487319874146. [Epub ahead of print] No abstract available.
PMID: 31480874 Free Article
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Ba H, Xu L, Peng H, Li X, Lin Y, Wang H, Qin Y.
Front Pediatr. 2019 Sep 3;7:361. doi: 10.3389/fped.2019.00361. eCollection 2019.
PMID: 31552206 Free PMC Article
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White BR, Rogers LS, Kirschen MP.
Curr Opin Pediatr. 2019 Sep 2. doi: 10.1097/MOP.0000000000000829. [Epub ahead of print]
PMID: 31483331
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Cahill TJ, Jewell PD, Denne L, Franklin RC, Frigiola A, Orchard E, Prendergast BD.
Am Heart J. 2019 Sep;215:70-77. doi: 10.1016/j.ahj.2019.05.014. Epub 2019 Jun 14.
PMID: 31299559
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Imperial-Perez F, Heilemann MV.
Am J Crit Care. 2019 Sep;28(5):354-360. doi: 10.4037/ajcc2019887.
PMID: 31474605
Select item 31301121
- Abernethy malformation: Our experience from a tertiary cardiac care center and review of literature.
Azad S, Arya A, Sitaraman R, Garg A.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):240-247. doi: 10.4103/apc.APC_185_18. Review.
PMID: 31516281 Free PMC Article
Select item 31079070
Häcker AL, Reiner B, Oberhoffer R, Hager A, Ewert P, Müller J.
Arch Dis Child. 2019 Sep;104(9):851-856. doi: 10.1136/archdischild-2018-316444. Epub 2019 May 11.
PMID: 31079070
Select item 30824490
Cloete E, Sadler L, Bloomfield FH, Crengle S, Percival T, Gentles TL.
Arch Dis Child. 2019 Sep;104(9):857-862. doi: 10.1136/archdischild-2018-315887. Epub 2019 Mar 1.
PMID: 30824490
Select item 31139902
Harrison TM.
Birth Defects Res. 2019 Sep 1;111(15):1128-1140. doi: 10.1002/bdr2.1517. Epub 2019 May 17. Review.
PMID: 31099484
Select item 30277407
Pasquali SK, Kaltman JR, Gaynor JW, McCrindle BW, Newburger JW, Anderson BR, Scheurer MA, Pinto NM, Anderson JB, Oster ME, Jacobs JP, Marino BS, Mery CM, Pearson GD.
Cardiol Young. 2019 Sep;29(9):1121-1126. doi: 10.1017/S104795111900163X. Epub 2019 Aug 6.
PMID: 31385565
Select item 31379319
Ordoñez MV, Moharem-Elgamal S, Bedair R.
Cardiol Young. 2019 Sep;29(9):1202-1205. doi: 10.1017/S1047951119001677. Epub 2019 Aug 5.
PMID: 31379319
Select item 31379312
Karatza A, Mylonas KS, Tzifa A.
Cardiol Young. 2019 Sep;29(9):1208-1210. doi: 10.1017/S1047951119001707. Epub 2019 Aug 5.
PMID: 31379312
Select item 31378215
van der Mheen M, Meentken MG, van Beynum IM, van der Ende J, van Galen E, Zirar A, Aendekerk EWC, van den Adel TPL, Bogers AJJC, McCusker CG, Hillegers MHJ, Helbing WA, Utens EMWJ.
Cardiol Young. 2019 Sep;29(9):1172-1182. doi: 10.1017/S1047951119001732. Epub 2019 Aug 5.
PMID: 31378215
Select item 31102479
Bidhult S, Hedström E, Carlsson M, Töger J, Steding-Ehrenborg K, Arheden H, Aletras AH, Heiberg E.
Clin Physiol Funct Imaging. 2019 Sep;39(5):327-338. doi: 10.1111/cpf.12582. Epub 2019 Jun 6.
PMID: 31102479
Select item 31230756
Matsuno S, Tsuji M, Hikita R, Matsumoto T, Baba Y, Moriyama K.
Congenit Anom (Kyoto). 2019 Sep;59(5):162-168. doi: 10.1111/cga.12316. Epub 2018 Nov 4.
PMID: 30315601
Select item 31351549
Wang J, Cao H, Sun D, Qi Z, Guo C, Peng W, Sun Y, Xie Y, Liu X, Li B, Luo Y, Pan Y, Li Y, Zhang L.
Environ Res. 2019 Sep;176:108531. doi: 10.1016/j.envres.2019.108531. Epub 2019 Jun 11.
PMID: 31226628
Select item 31504403
Pontailler M, Haidar M, Méot M, Moreau de Bellaing A, Gaudin R, Houyel L, Metton O, Moceri P, Bonnet D, Vouhé P, Raisky O.
Eur J Cardiothorac Surg. 2019 Sep 1;56(3):541-548. doi: 10.1093/ejcts/ezz085.
PMID: 30897200
Select item 30879050
Shi Y, Li Y, Wang Y, Zhuang J, Wang H, Hu M, Mo X, Yue S, Chen Y, Fan X, Chen J, Cai W, Zhu X, Wan Y, Zhong Y, Ye X, Li F, Zhou Z, Dai G, Luo R, Ocorr K, Jiang Z, Li X, Zhu P, Wu X, Yuan W.
Genet Test Mol Biomarkers. 2019 Sep;23(9):601-609. doi: 10.1089/gtmb.2019.0085. Epub 2019 Aug 6.
PMID: 31386585
Select item 31352143
Quarello E.
Gynecol Obstet Fertil Senol. 2019 Sep;47(9):680-688. doi: 10.1016/j.gofs.2019.07.009. Epub 2019 Jul 25. French.
PMID: 31352143
Select item 31109891
Kalayinia S, Maleki M, Rokni-Zadeh H, Changi-Ashtiani M, Ahangar H, Biglari A, Shahani T, Mahdieh N.
J Clin Lab Anal. 2019 Sep;33(7):e22923. doi: 10.1002/jcla.22923. Epub 2019 May 22.
PMID: 31115957
Select item 30938874
So SCY, Li WHC, Ho KY.
J Clin Nurs. 2019 Sep;28(17-18):3158-3167. doi: 10.1111/jocn.14864. Epub 2019 Apr 21.
PMID: 30938874
Select item 31548736
Hansmann G, Koestenberger M, Alastalo TP, Apitz C, Austin ED, Bonnet D, Budts W, D’Alto M, Gatzoulis MA, Hasan BS, Kozlik-Feldmann R, Kumar RK, Lammers AE, Latus H, Michel-Behnke I, Miera O, Morrell NW, Pieles G, Quandt D, Sallmon H, Schranz D, Tran-Lundmark K, Tulloh RMR, Warnecke G, Wåhlander H, Weber SC, Zartner P.
J Heart Lung Transplant. 2019 Sep;38(9):879-901. doi: 10.1016/j.healun.2019.06.022. Epub 2019 Jun 21.
PMID: 31495407
Select item 31324444
Zhong L, Schrauben EM, Garcia J, Uribe S, Grieve SM, Elbaz MSM, Barker AJ, Geiger J, Nordmeyer S, Marsden A, Carlsson M, Tan RS, Garg P, Westenberg JJM, Markl M, Ebbers T.
J Magn Reson Imaging. 2019 Sep;50(3):677-681. doi: 10.1002/jmri.26858. Epub 2019 Jul 17.
PMID: 31317587
Select item 30838716
Bishop MN, Gise JE, Donati MR, Shneider CE, Aylward BS, Cohen LL.
J Pediatr Psychol. 2019 Sep 1;44(8):980-987. doi: 10.1093/jpepsy/jsz026.
PMID: 31329926
Select item 31290975
Williams TS, McDonald KP, Roberts SD, Chau V, Seed M, Miller SP, Sananes R.
J Pediatr Psychol. 2019 Sep 1;44(8):924-936. doi: 10.1093/jpepsy/jsz055.
PMID: 31290975
Select item 31069392
Siciliano RE, Prussien KV, Lee CA, Patel NJ, Murphy LK, Compas BE, Jordan LC.
J Pediatr Psychol. 2019 Sep 1;44(8):937-947. doi: 10.1093/jpepsy/jsz021.
PMID: 31069392
Select item 30814038
Bubberman JM, van Zoonen A, Bruggink JLM, van der Heide M, Berger RMF, Bos AF, Kooi EMW, Hulscher JBF.
J Pediatr Surg. 2019 Sep;54(9):1755-1760. doi: 10.1016/j.jpedsurg.2018.11.012. Epub 2018 Dec 13.
PMID: 30635129
Select item 31443808
Priya S, Nagpal P, Sharma A, Pandey NN, Jagia P.
J Thorac Imaging. 2019 Sep;34(5):W89-W99. doi: 10.1097/RTI.0000000000000396.
PMID: 30801451
Select item 31380593
Shen Q, Chen W, Liu J, Liang Q.
Life Sci. 2019 Sep 1;232:116546. doi: 10.1016/j.lfs.2019.116546. Epub 2019 Jun 6.
PMID: 31176777
Select item 31446699
Zhang QJ, Wang DY, Wang QJ.
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Sep;33(9):835-839. doi: 10.13201/j.issn.1001-1781.2019.09.009. Review. Chinese.
PMID: 31446699
Select item 31446696
Qiu SW, Yuan YY.
Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2019 Sep;33(9):820-824. doi: 10.13201/j.issn.1001-1781.2019.09.006. Review. Chinese.
PMID: 31446696
Select item 31081250
Yuan XC, Liu M, Hu J, Zeng X, Zhou AY, Chen L.
Medicine (Baltimore). 2019 Sep;98(38):e17141. doi: 10.1097/MD.0000000000017141.
PMID: 31567953 Free Article
Select item 31490396
Vayngortin T, Rosenfeld H, Mansour K.
Pediatr Emerg Care. 2019 Sep;35(9):e172-e173. doi: 10.1097/PEC.0000000000001162.
PMID: 28463946
Select item 31033906
Rodriguez-Gonzalez M, Benavente-Fernandez I, Castellano-Martinez A.
Cardiol Young. 2019 Sep 30:1-2. doi: 10.1017/S1047951119002348. [Epub ahead of print]
PMID: 31566150
Select item 31568572
Kühnisch J, Herbst C, Al-Wakeel-Marquard N, Dartsch J, Holtgrewe M, Baban A, Mearini G, Hardt J, Kolokotronis K, Gerull B, Carrier L, Beule D, Schubert S, Messroghli D, Degener F, Berger F, Klaassen S.
Clin Genet. 2019 Sep 30. doi: 10.1111/cge.13645. [Epub ahead of print]
PMID: 31568572
Select item 31574005
Cohen JA, Almodovar MC.
Curr Opin Cardiol. 2019 Sep 30. doi: 10.1097/HCO.0000000000000692. [Epub ahead of print]
PMID: 31574005
Select item 31574003
Sugiyama K, Horigome H, Lin L, Murakami T, Shiono J, Yamashiro Y, Matsuura H, Yoda H, Yanagisawa H.
Mol Genet Genomic Med. 2019 Sep 27:e986. doi: 10.1002/mgg3.986. [Epub ahead of print]
PMID: 31560829 Free Article
Select item 31567621
Sallmon H, Moledina S, Albert DC, Beghetti M, Berger RMF, Bonnet D, Bukova M, Koestenberger M, Meinel K, Reinhardt Z, Tulloh RMR, de Wolf D, Hansmann G.
Cardiol Young. 2019 Sep 26:1-5. doi: 10.1017/S104795111900235X. [Epub ahead of print]
PMID: 31554525
Select item 31556238
Fan L, Zhang H, Cai J, Yang L, Wei D, Yu J, Fan J, Song L, Ma W, Lou Y.
Am J Hypertens. 2019 Sep 24;32(10):1021-1029. doi: 10.1093/ajh/hpz103.
PMID: 31278892
Select item 31549603
Tremoulet AH, Jain S, Jone PN, Best BM, Duxbury EH, Franco A, Printz B, Dominguez SR, Heizer H, Anderson MS, Glodé MP, He F, Padilla RL, Shimizu C, Bainto E, Pancheri J, Cohen HJ, Whitin JC, Burns JC.
J Pediatr. 2019 Sep 24. pii: S0022-3476(19)30972-2. doi: 10.1016/j.jpeds.2019.07.064. [Epub ahead of print]
PMID: 31561960
Select item 31547773
Maia MR, Castela E, Pires A, Lapão LV.
BMC Health Serv Res. 2019 Sep 23;19(1):681. doi: 10.1186/s12913-019-4511-5.
PMID: 31547824 Free PMC Article
Select item 31542952
de Klerk JCA, van Paassen N, van Beynum IM, Flint RB, Reiss IKM, Simons SHP.
J Matern Fetal Neonatal Med. 2019 Sep 23:1-7. doi: 10.1080/14767058.2019.1667323. [Epub ahead of print]
PMID: 31510826
Select item 31473233
Allen KY, Jones S, Jackson T, DeCost G, Stephens P, Hanna BD, Cohen MS, Smith-Whitley K, Mercer-Rosa L, Natarajan SS.
Pediatr Cardiol. 2019 Sep 21. doi: 10.1007/s00246-019-02202-3. [Epub ahead of print]
PMID: 31542803
Select item 31564593
Shao S, Luo C, Zhou K, Hua Y, Wu M, Liu L, Liu X, Wang C.
Pediatr Rheumatol Online J. 2019 Sep 18;17(1):65. doi: 10.1186/s12969-019-0368-8.
PMID: 31533770 Free PMC Article
Select item 31529765
Ritter A, Bedoukian E, Berger JH, Copenheaver D, Gray C, Krantz I, Izumi K, Juusola J, Leonard J, Lin K, Medne L, Santani A, Skraban C, Yang S, Ahrens-Nicklas RC.
Genet Med. 2019 Sep 17. doi: 10.1038/s41436-019-0654-3. [Epub ahead of print]
PMID: 31527676
Select item 31540780
Bratt EL, Järvholm S, Ekman-Joelsson BM, Johannsmeyer A, Carlsson SÅ, Mattsson LÅ, Mellander M.
Cardiol Young. 2019 Sep 16:1-7. doi: 10.1017/S1047951119001781. [Epub ahead of print]
PMID: 31522698
Select item 31529165
Knirsch W, Heye KN, Tuura RO, Hahn A, Wetterling K, Latal B, Schranz D, Reich B.
Int J Cardiol. 2019 Sep 15;291:42-44. doi: 10.1016/j.ijcard.2019.03.055. Epub 2019 Mar 27.
PMID: 30952528
Select item 30772012
Padalino MA, Franchetti N, Sarris GE, Hazekamp M, Carrel T, Frigiola A, Horer J, Roussin R, Cleuziou J, Meyns B, Fragata J, Telles H, Polimenakos AC, Francois K, Veshti A, Salminen J, Rocafort AG, Nosal M, Vedovelli L, Protopapas E, Tumbarello R, Merola A, Pegoraro C, Motta R, Boccuzzo G, Sojak V, Rito ML, Caldaroni F, Corrado D, Basso C, Stellin G.
Int J Cardiol. 2019 Sep 15;291:189-193. doi: 10.1016/j.ijcard.2019.02.007. Epub 2019 Feb 10.
PMID: 30772012 Free Article
Select item 31292610
Gupta A, Husain N, Tannous P, Hauck A.
Pediatr Cardiol. 2019 Sep 14. doi: 10.1007/s00246-019-02192-2. [Epub ahead of print]
PMID: 31522266
Select item 31525336
Mandawat A, Eberly L, Border W.
Curr Cardiol Rep. 2019 Sep 13;21(10):128. doi: 10.1007/s11886-019-1212-y. Review.
PMID: 31520151
Select item 31520399
Berhane H, Ruh A, Husain N, Robinson JD, Rigsby CK, Markl M.
J Magn Reson Imaging. 2019 Sep 12. doi: 10.1002/jmri.26916. [Epub ahead of print]
PMID: 31515865
Select item 31513548
Hill GD, Tanem J, Ghanayem N, Rudd N, Ollberding NJ, Lavoie J, Frommelt M.
Ann Thorac Surg. 2019 Sep 10. pii: S0003-4975(19)31351-7. doi: 10.1016/j.athoracsur.2019.07.062. [Epub ahead of print]
PMID: 31518582
Select item 31506079
Cantinotti M, Giordano R, Marrone C, Franchi E, Koestenberger M, Assanta N.
Pediatr Cardiol. 2019 Sep 10. doi: 10.1007/s00246-019-02204-1. [Epub ahead of print]
PMID: 31506732
Select item 31506731
Ibrahim A, Borrelli N, Krupickova S, Sabatino J, Avesani M, Paredes J, Josen M, D’Ascenzi F, Mondillo S, Di Salvo G.
Am J Cardiol. 2019 Sep 9. pii: S0002-9149(19)31011-2. doi: 10.1016/j.amjcard.2019.08.042. [Epub ahead of print]
PMID: 31586532
Select item 31586531
Barrera CA, Saul D, Rapp JB, Smith CL, White AM, Biko DM, Otero HJ.
Int J Cardiovasc Imaging. 2019 Sep 9. doi: 10.1007/s10554-019-01693-8. [Epub ahead of print]
PMID: 31502067
Select item 31499571
Steele JM, Komarlu R, Worley S, Alsaied T, Statile C, Erenberg FG.
Congenit Heart Dis. 2019 Sep 6. doi: 10.1111/chd.12829. [Epub ahead of print]
PMID: 31489778
Select item 31490577
Bhat AH, Trent E, Kapur RP, Permut L.
Echocardiography. 2019 Sep 6. doi: 10.1111/echo.14475. [Epub ahead of print]
PMID: 31490577
Select item 31486350
Yoldaş T, Beyazal M, Örün UA.
Cardiol Young. 2019 Sep 5:1-2. doi: 10.1017/S1047951119002105. [Epub ahead of print]
PMID: 31486350
Select item 31486566
Oh J, Song IK, Cho J, Yun TJ, Park CS, Choi JM, Gwak M, Shin WJ.
Pediatr Cardiol. 2019 Sep 3. doi: 10.1007/s00246-019-02195-z. [Epub ahead of print]
PMID: 31482237
Select item 31482236
Kadoya T, Sakakibara A, Kitayama K, Yamada Y, Higuchi S, Kawakita R, Kawasaki Y, Fujino M, Murakami Y, Shimura M, Murayama K, Ohtake A, Okazaki Y, Koga Y, Yorifuji T.
J Pediatr Endocrinol Metab. 2019 Sep 2. pii: /j/jpem.ahead-of-print/jpem-2019-0205/jpem-2019-0205.xml. doi: 10.1515/jpem-2019-0205. [Epub ahead of print]
PMID: 31473688
Select item 31530356
Berger-Caron F, Piedboeuf B, Morissette G, Simonyan D, Chétaille P, Pellerin A, Hébert A.
Am J Perinatol. 2019 Sep;36(11):1142-1149. doi: 10.1055/s-0038-1676483. Epub 2018 Dec 14.
PMID: 30551229
Select item 31268349
Mohanty S, Pavithran S, Agarwal R, Sivakumar K.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):339-341. doi: 10.4103/apc.APC_179_18.
PMID: 31516299 Free PMC Article
Select item 31516298
Sheth R, Singh AS, Pavithran S, Sivakumar K.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):333-335. doi: 10.4103/apc.APC_188_18.
PMID: 31516297 Free PMC Article
Select item 31516296
Stéphanie P, Catherine B, Thierry S, Jean-Luc V, Isabelle L, Sara S, Christophe V, Marie-Cécile N.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):325-328. doi: 10.4103/apc.APC_136_18.
PMID: 31516295 Free PMC Article
Select item 31516294
Aggarwal N, Joshi RK, Paktin N, Agarwal M, Joshi R.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):302-304. doi: 10.4103/apc.APC_102_18.
PMID: 31516288 Free PMC Article
Select item 31516286
Agati S, Sousa CG, Calvaruso FD, Zanai R, Campanella I, Poli D, Di Pino A, Borro L, Iorio FS, Raponi M, Anderson RH, Reali S, De Zorzi A, Secinaro A.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):248-253. doi: 10.4103/apc.APC_89_18.
PMID: 31516282 Free PMC Article
Select item 31516281
Chang AC.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):191-194. doi: 10.4103/apc.APC_55_19. No abstract available.
PMID: 31516273 Free PMC Article
Select item 31079070
Häcker AL, Reiner B, Oberhoffer R, Hager A, Ewert P, Müller J.
Arch Dis Child. 2019 Sep;104(9):851-856. doi: 10.1136/archdischild-2018-316444. Epub 2019 May 11.
PMID: 31079070
Select item 31139902
Alp H, Elmacı AM, Alp EK, Say B.
Cardiol Young. 2019 Sep;29(9):1189-1195. doi: 10.1017/S1047951119001835.
PMID: 31451130
Select item 31451126
McCloud AK, Lowisz J, Roberson DA, Lefaiver CA, Penk JS.
Cardiol Young. 2019 Sep;29(9):1149-1159. doi: 10.1017/S1047951119001641. Epub 2019 Aug 15.
PMID: 31412970
Select item 31391137
Robinson J, Huskey D, Schalley S, Wratchford D, Hammel J, Weaver MS.
Cardiol Young. 2019 Sep;29(9):1143-1148. doi: 10.1017/S1047951119001586. Epub 2019 Aug 8.
PMID: 31391137
Select item 31385565
Pasquali SK, Kaltman JR, Gaynor JW, McCrindle BW, Newburger JW, Anderson BR, Scheurer MA, Pinto NM, Anderson JB, Oster ME, Jacobs JP, Marino BS, Mery CM, Pearson GD.
Cardiol Young. 2019 Sep;29(9):1121-1126. doi: 10.1017/S104795111900163X. Epub 2019 Aug 6.
PMID: 31385565
Select item 31379312
Karatza A, Mylonas KS, Tzifa A.
Cardiol Young. 2019 Sep;29(9):1208-1210. doi: 10.1017/S1047951119001707. Epub 2019 Aug 5.
PMID: 31379312
Select item 31378215
Cochet H, Iriart X, Allain-Nicolaï A, Camaioni C, Sridi S, Nivet H, Fournier E, Dinet ML, Jalal Z, Laurent F, Montaudon M, Thambo JB.
Eur Heart J Cardiovasc Imaging. 2019 Sep 1;20(9):990-1003. doi: 10.1093/ehjci/jez068.
PMID: 30993335 Free PMC Article
Select item 30897200
Hansmann G, Koestenberger M, Alastalo TP, Apitz C, Austin ED, Bonnet D, Budts W, D’Alto M, Gatzoulis MA, Hasan BS, Kozlik-Feldmann R, Kumar RK, Lammers AE, Latus H, Michel-Behnke I, Miera O, Morrell NW, Pieles G, Quandt D, Sallmon H, Schranz D, Tran-Lundmark K, Tulloh RMR, Warnecke G, Wåhlander H, Weber SC, Zartner P.
J Heart Lung Transplant. 2019 Sep;38(9):879-901. doi: 10.1016/j.healun.2019.06.022. Epub 2019 Jun 21.
PMID: 31495407
Select item 31324444
Zhong L, Schrauben EM, Garcia J, Uribe S, Grieve SM, Elbaz MSM, Barker AJ, Geiger J, Nordmeyer S, Marsden A, Carlsson M, Tan RS, Garg P, Westenberg JJM, Markl M, Ebbers T.
J Magn Reson Imaging. 2019 Sep;50(3):677-681. doi: 10.1002/jmri.26858. Epub 2019 Jul 17.
PMID: 31317587
Select item 30838716
Yücel M, Alp H, Yorulmaz A, Karaarslan S, Baysal T.
Turk Kardiyol Dern Ars. 2019 Sep;47(6):466-475. doi: 10.5543/tkda.2019.33558.
PMID: 31483301 Free Article
Select item 31483299
Loke YH, Capuano F, Mandell J, Cross RR, Cronin I, Mass P, Balaras E, Olivieri LJ.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):572-581. doi: 10.1177/2150135119861358.
PMID: 31496415
Select item 31496410
Kadam SV, Tailor KB, Joshi VH, Rao SG.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):351-353. doi: 10.4103/apc.APC_108_18. No abstract available.
PMID: 31516305 Free PMC Article
Select item 31516304
Patel A, Bharani A, Sharma M, Bhagwat A, Ganguli N, Chouhan DS.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):349. doi: 10.4103/apc.APC_90_19. No abstract available.
PMID: 31516303 Free PMC Article
Select item 31516302
Al-Mendalawi MD.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):348. doi: 10.4103/apc.APC_64_19. No abstract available.
PMID: 31516302 Free PMC Article
Select item 31516301
Soni N, Jain SK, Kumar A, Kadian R, Li S.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):345-347. doi: 10.4103/apc.APC_69_18.
PMID: 31516301 Free PMC Article
Select item 31516300
Stéphanie P, Catherine B, Thierry S, Jean-Luc V, Isabelle L, Sara S, Christophe V, Marie-Cécile N.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):325-328. doi: 10.4103/apc.APC_136_18.
PMID: 31516295 Free PMC Article
Select item 31516294
Hansen G, Holt T, Dmytrowich J.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):315-317. doi: 10.4103/apc.APC_189_18.
PMID: 31516292 Free PMC Article
Select item 31516291
Garcia RU, Safa R, Evans C, Alessio D, Delius R, Shehata B.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):298-301. doi: 10.4103/apc.APC_144_18.
PMID: 31516287 Free PMC Article
Select item 31516286
Saini N, Kumar D, Swarnim S, Bhatt D, Kishore S.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):195-200. doi: 10.4103/apc.APC_60_18.
PMID: 31516274 Free PMC Article
Select item 31516273
Chang AC.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):191-194. doi: 10.4103/apc.APC_55_19. No abstract available.
PMID: 31516273 Free PMC Article
ACHD Featured Articles in association with ISACHD
Adult Congenital Heart Reviews of September 2019 manuscripts (sponsored by ISACHD)
ACHD Reviews of September 2019 Manuscripts – Sponsored by ISACHD
Determinants of Left Ventricular Dysfunction and Remodeling in Patients With Corrected Tetralogy of Fallot.
Andrade AC, Jerosch-Herold M, Wegner P, Gabbert DD, Voges I, Pham M, Shah R, Hedderich J, Kramer HH, Rickers C.
J Am Heart Assoc. 2019 Sep 3;8(17):e009618. doi: 10.1161/JAHA.118.009618. Epub 2019 Aug 31.
PMID: 31474177 Free PMC Article
Select item 31450994
Take-Home Points:
- Both impaired systolic and diastolic dysfunction of the LV, adverse remodeling with ECM expansion, myocardial atrophy and a reduced mass/volume ratio are seen in asymptomatic (NYHA I) with rTOF.
- These markers of LV systolic dysfunction are associated with reduced peak oxygen consumption during CPET and thus a predictor of poorer outcome in rTOF.
Commentary from Dr. Blanche Cupido (Cape Town, South Africa), section editor of ACHD Journal Watch: In patients with repaired Tetralogy of Fallot (rTOF), pulmonary regurgitation and RV dilatation and function is usually the focus at clinical follow-up. LV dysfunction too has been found to be a predictor of death and sustained ventricular tachycardia in rTOF. This is a cross-sectional study aiming to assess the prevalence of LV dysfunction in asymptomatic (NYHA I) patients with rTOF and to identify the associations between right heart markers of pathologic remodeling and LV remodeling. Furthermore, in a subset of patients, cardiopulmonary exercise testing was done and the effect of LV remodeling and dysfunction on age-and sex-adjusted peak exercise parameters were assessed.
This was a prospective cross-sectional study at a tertiary center in Sao Paulo, Brazil. One hundred and three consecutive patients with rTOF and NYHA I were enrolled between January 2012 and August 2016. Baseline characteristics are displayed in Table1 below.
Of the 103 patients enrolled with rTOF, 43 were female. Patients were studied at 15.1±8.7 years after surgical repair. Twenty patients had initial shunt implantations, 49% (n=51) had a transannular patch repair. Furthermore, 24% (n=25) had re-operations for mainly PR. There were no differences in age, weight, height, BSA and blood pressure between patients and healthy controls.
Referring to table 2 above, RV mass index, indexed RV end-systolic and end-diastolic volumes as well as RV mass/volume ratios were significantly higher in rTOF patients compared to healthy controls. In patients with rTOF, LV EF, LV mass index, LV mass/volume ratio and LV/RV mass ratio were markedly reduced compared to healthy controls. LVEDVi however did not differ between subjects and controls but correlated with RVEDVi (r=0.36, p<0;.001). LA volumes and function were also decreased compared to controls.
Table 3 shows, for each LV parameter, the proportion of patients with rTOF with values falling out of the corresponding age related 95% CI’s. In patients with rTOF, LVEF correlated with RVEF (p=0.41, p<0.001; 95%CI 0.26-0.54) and RV mass/volume ratio (p=0.33, P<0.001). In total, 23% had moderate LVEF impairment (EF 35%-45%) and 41% had mild dysfunction (EF 45-55%), 36% had normal LVEF.
Figure 2 A above shows that LV systolic dysfunction is associated with remodeling of the RV, as per RV mass-to-volume-ratio. This remained significant in a multivariate module. LV systolic dysfunction is also associated with RVESVi.
Figure 4 shows that 28% of all patients with rTOF had LV mass / volume ratio below the age-specific 5th percentile level in healthy controls.
Figure 4A
Late Gadolinium enhancement (LGE) was performed in 65 of the cohort. In 95% of these patients, the site was the ventricular septum, 46% showed LGE in the RVOT and 13.8% in other areas of the heart but not the free wall.
Cardiopulmonary testing results (CPET) were available in 70 patients with rTOF. VO2max was less than the 3rd centile in 29% of patients.
External Validation of 3 Risk Scores in Adults with Congenital Heart Disease.
Ramchandani BK, Polo L, Sánchez R, Rey J, González Á, Díez J, Aroca Á.
Korean Circ J. 2019 Sep;49(9):856-863. doi: 10.4070/kcj.2019.0015. Epub 2019 May 7.
PMID: 31165593 Free PMC Article
Select item 31582699
Take-Home Points:
- There was no significant difference in discrimination between the 3 mortality predictors. However, calibration showed RACHS 1 underpredicted mortality, Aristotle overpredicted mortality and Euro 1 was mis-calibrated.
Commentary from Dr. Helen Parry (Leeds UK), section editor of ACHD Journal Watch:
Aim: To compare RACHS-1, Aristotle and EURO-1 risk scores in predicting in hospital mortality for patients undergoing surgery for congenital heart disease in adulthood
Methods: The study was performed retrospectively in a single centre in Spain, looking at operations performed over a 26 year period. The primary end-point was 30 day mortality, looked at each of the above scores and looked at correlation with mortality. This was assessed by discrimination (ability to predict death, using the area under the curve) and calibration (accuracy of the prediction).
Results: Six hundred and eight procedures were performed on adult patients with congenital heart disease. There was no significant difference in discrimination between the 3 mortality predictors. However, calibration showed RACHS 1 under predicted mortality, Aristotle over predicted mortality and Euro 1 was mis-calibrated.
Discussion: The authors suggest that RACHS 1 and Aristotle are superior to Euro 1 in congenital heart disease patients. RACHS 1 and Aristotle take greater account of the complexity of patients with congenital heart disease e.g. those with genetic disorders. However, RACHS 1 and Aristotle also look at birth weight and prematurity, which are less relevant in adults relative to paediatrics.
Strengths of the study:
- Large sample size
- Representative case mix including high percentage of re-do sternotomies
Weaknesses of the study:
- Single centre and retrospective
- It would also have been useful to have more details on the mortalities e.g. why did a 32 year old male attending for a PVR die of a myocardial infarction?
Assessment and Implications of Right Ventricular Afterload in Tetralogy of Fallot.
Egbe AC, Taggart NW, Reddy YNV, Sufian M, Banala K, Vojjini R, Najam M, Osman K, Obokata M, Borlaug BA.
Am J Cardiol. 2019 Sep 9. pii: S0002-9149(19)31003-3. doi: 10.1016/j.amjcard.2019.08.035. [Epub ahead of print]
PMID: 31586531
Select item 31501090
Take-Home Points:
- High RV pressure after repair of tetralogy of Fallot (TOF) adversely affects clinical outcomes.
- Invasively measured right ventricular systolic pressure (RVSP) and TOF with pulmonary atresia are independent risk factor for death and/ or heart transplant.
- Doppler-derived RVSP has good correlation between invasively measured RVSP and is independently predictive of death and / or heart transplant.
Commentary by Dr. M.C. Leong (Kuala Lumpur, Malaysia), section editor of ACHD Journal Watch: In the attempt to preserve the pulmonary valve during surgery, surgeons usually leave patients with residual right ventricular outflow tract (RVOT) obstruction either at the pulmonary annular or perivalvular level after the repair of tetralogy of Fallot (TOF). Often, this is seen as benign as the residual RVOT is usually not high and in fact, may even promote development of restrictive right ventricular physiology which may mitigate progressive right ventricular dilatation. However, if the right ventricular systolic pressure is left high for a chronic period of time, its long term effect onto the right ventricle is unknown. This paper studied the effect of significant elevated right ventricular afterload, whether it independently affects the clinical outcomes of patients with TOF.
This is a retrospective study, looking at 266 patients who underwent cardiac catheterization during follow up. Of these, 175 (66%) patients had significant RVOT obstruction, which was defined as a peak-to-peak gradient of greater than 36mmHg, on direct measurement. Within this cohort, 212 patients had echocardiography within 48 hours of the cardiac catheterization.
These patients were followed up for 12.9 ± 7.3 years from the time of invasive study. During this period 35 (13%) patients died at a mean age of 49 ± 14 years. Of these, 27 patients had significant RVOT obstruction while 8 patients did not. There was no significant difference in mortality between patients with versus without significant RVOT obstruction. Invasively measured RVSP and TOF-pulmonary atresia were independent risk factors for death and/or heart transplant.
There was a strong correlation between the invasively measured right ventricular systolic pressure (RVSP) and that of echocardiographic Doppler-derived, with a mean difference of +6mmHg suggesting that follow up using echocardiography is accurate yet noninvasive. Doppler-derived RSVP was independently predictive of death and / or transplant.
It is interesting to note that TOF-pulmonary atresia itself was a risk factor for death and heart failure. With increasing attempts of unifocalization of the aorto-pulmonary collaterals and incorporating them into the pulmonary arterial tree as well as total repair when the pulmonary arterial size is less than desired, many patients are left with high RVSP and this paper underscores the effects of having a high RVSP in this group of patients. A caveat to this paper is the fact that patients who undergo invasive investigation are those with poorer hemodynamics and inherently are at a higher risk of death and heart failure. Hence many of these patients are higher risk patients compared to the general TOF population.
ACHD Sept 2019
Häcker AL, Oberhoffer R, Hager A, Ewert P, Müller J.
Congenit Heart Dis. 2019 Sep 26. doi: 10.1111/chd.12845. [Epub ahead of print]
PMID: 31556238
Select item 31557345
Lang IM.
Wien Klin Wochenschr. 2019 Sep 23. doi: 10.1007/s00508-019-1529-y. [Epub ahead of print] Review.
PMID: 31549230
Select item 31544351
Holbein CE, Peugh J, Veldtman GR, Apers S, Luyckx K, Kovacs AH, Thomet C, Budts W, Enomoto J, Sluman MA, Lu CW, Jackson JL, Khairy P, Cook SC, Chidambarathanu S, Alday L, Eriksen K, Dellborg M, Berghammer M, Johansson B, Mackie AS, Menahem S, Caruana M, Soufi A, Fernandes SM, White K, Callus E, Kutty S, Moons P; APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD).
Eur J Prev Cardiol. 2019 Sep 17:2047487319876231. doi: 10.1177/2047487319876231. [Epub ahead of print]
PMID: 31529991
Select item 31530101
Farr SL, Downing KF, Ailes EC, Gurvitz M, Koontz G, Tran EL, Alverson CJ, Oster ME.
J Am Heart Assoc. 2019 Sep 17;8(18):e013608. doi: 10.1161/JAHA.119.013608. Epub 2019 Sep 12.
PMID: 31510829 Free Article
Select item 31540762
Connor B, Osborne W, Peir G, Smith M, John A.
Am J Cardiol. 2019 Sep 15;124(6):947-951. doi: 10.1016/j.amjcard.2019.05.073. Epub 2019 Jun 25.
PMID: 31327487
Select item 31151765
Ueno R, Yagi S, Bando M, Sata M.
Intern Med. 2019 Sep 15;58(18):2749-2750. doi: 10.2169/internalmedicine.2455-18. Epub 2019 Jun 7. No abstract available.
PMID: 31178488 Free Article
Select item 31521197
Bokma JP, Daily JA, Kovacs AH, Oechslin EN, Baumgartner H, Khairy P, Mulder BJM, Veldtman GR.
Cardiol Young. 2019 Sep 10:1-5. doi: 10.1017/S1047951119002063. [Epub ahead of print]
PMID: 31502529
Select item 31506869
Sliwa K, Baris L, Sinning C, Zengin-Sahm E, Gumbiene L, Yaseen IF, Youssef G, Johnson M, Al-Farhan H, Lelonek M, Hall R, Roos-Hesselink J.
JACC Heart Fail. 2019 Sep 7. pii: S2213-1779(19)30731-0. doi: 10.1016/j.jchf.2019.09.001. [Epub ahead of print]
PMID: 31511192
Select item 31494702
Willems R, de Hosson M, De Backer J, Annemans L.
Cardiol Young. 2019 Sep 6:1-7. doi: 10.1017/S1047951119002245. [Epub ahead of print]
PMID: 31489832
Select item 31489778
Johnson B, Buelow M, Earing M, Cohen S, Bartz P, Ginde S.
Congenit Heart Dis. 2019 Sep 6. doi: 10.1111/chd.12839. [Epub ahead of print]
PMID: 31489771
Select item 31489769
Reekie J.
Heart. 2019 Sep 6. pii: heartjnl-2019-315727. doi: 10.1136/heartjnl-2019-315727. [Epub ahead of print] No abstract available.
PMID: 31492700
Select item 31492699
Chen YC, Weng KP, Chien KJ, Chen BH, Hsieh KS, Ta IH, Huang SH, Peng HH, Huang JS, Wu MT.
J Chin Med Assoc. 2019 Sep 6. doi: 10.1097/JCMA.0000000000000185. [Epub ahead of print]
PMID: 31517771
Select item 31492776
Colpo A, Marson P, Pavanello F, Tison T, Gervasi MT, Zambon A, Ruffatti A, De Silvestro G, Hoxha A.
Transfus Apher Sci. 2019 Sep 5. pii: S1473-0502(19)30185-5. doi: 10.1016/j.transci.2019.07.009. [Epub ahead of print]
PMID: 31522920
Select item 31487969
Fricke TA, Konstantinov IE, Grigg LE, Zentner D.
Heart Lung Circ. 2019 Sep 3. pii: S1443-9506(19)31411-8. doi: 10.1016/j.hlc.2019.07.016. [Epub ahead of print]
PMID: 31522930
Select item 31474177
Andrade AC, Jerosch-Herold M, Wegner P, Gabbert DD, Voges I, Pham M, Shah R, Hedderich J, Kramer HH, Rickers C.
J Am Heart Assoc. 2019 Sep 3;8(17):e009618. doi: 10.1161/JAHA.118.009618. Epub 2019 Aug 31.
PMID: 31474177 Free PMC Article
Select item 31450994
Kajimoto M, Nuri M, Isern NG, Robillard-Frayne I, Des Rosiers C, Portman MA.
J Am Heart Assoc. 2019 Sep 3;8(17):e013169. doi: 10.1161/JAHA.119.013169. Epub 2019 Aug 27.
PMID: 31450994 Free PMC Article
Select item 31431113
Geenen LW, van Grootel RWJ, Akman K, Baggen VJM, Menting ME, Eindhoven JA, Cuypers JAAE, Boersma E, van den Bosch AE, Roos-Hesselink JW.
J Am Heart Assoc. 2019 Sep 3;8(17):e013745. doi: 10.1161/JAHA.119.013745. Epub 2019 Aug 21.
PMID: 31431113 Free PMC Article
Select item 31478249
Egbe AC, Kothapalli S, Borlaug BA, Ammash NM, Najam M, Bajwa N, Tarek K, Matthew J, Connolly HM.
Am J Cardiol. 2019 Sep 1;124(5):803-807. doi: 10.1016/j.amjcard.2019.05.048. Epub 2019 Jun 7.
PMID: 31272701
Select item 31474605
De Rubeis G, Galea N, Ceravolo I, Dacquino GM, Carbone I, Catalano C, Francone M.
Br J Radiol. 2019 Sep;92(1101):20170868. doi: 10.1259/bjr.20170868. Epub 2019 Jul 18. Review.
PMID: 30277407
Select item 31385565
Cordina RL, Playford D, Lang I, Celermajer DS.
Heart Lung Circ. 2019 Sep;28(9):1351-1364. doi: 10.1016/j.hlc.2019.03.003. Epub 2019 Apr 30. Review.
PMID: 31109891
Select item 30904484
Neidenbach R, Achenbach S, Andonian C, Beckmann J, Biber S, Dittrich S, Ewert P, Freilinger S, Huntgeburth M, Nagdyman N, Oberhoffer R, Pieper L, von Kodolitsch Y, Weyand M, Bauer UMM, Kaemmerer H.
Herz. 2019 Sep;44(6):553-572. doi: 10.1007/s00059-019-4820-9. German.
PMID: 31263905
Select item 31197456
D’Alto M, Budts W, Diller GP, Mulder B, Egidy Assenza G, Oreto L, Ciliberti P, Bassareo PP, Gatzoulis MA, Dimopoulos K.
Int J Cardiol. 2019 Sep 1;290:156-161. doi: 10.1016/j.ijcard.2019.05.010. Epub 2019 May 4.
PMID: 31085083
Select item 31141298
Martínez-Quintana E, Rodríguez-Hernández JL, Rodríguez-González F, Riaño-Ruiz M, Fraguela-Medina C, Girolimetti A, Jiménez-Rodríguez S.
Int J Clin Pract. 2019 Sep;73(9):1-8. doi: 10.1111/ijcp.13378. Epub 2019 Jun 28.
PMID: 31141298
Select item 31089681
Gordon-Walker TT, Bove K, Veldtman G.
J Cardiol. 2019 Sep;74(3):223-232. doi: 10.1016/j.jjcc.2019.02.016. Epub 2019 Mar 28. Review.
PMID: 30928109
Select item 31343584
Li X, Chen N, Zhou X, Yang Y, Chen S, Song Y, Sun K, Du Q.
J Cardiopulm Rehabil Prev. 2019 Sep;39(5):299-307. doi: 10.1097/HCR.0000000000000420.
PMID: 31343584
Select item 31130315
Ait Ali L, Aquaro GD, Peritore G, Ricci F, De Marchi D, Emdin M, Passino C, Festa P.
J Magn Reson Imaging. 2019 Sep;50(3):779-786. doi: 10.1002/jmri.26684. Epub 2019 Mar 5.
PMID: 30838716
Select item 30714251
Uzark K, Afton K, Yu S, Lowery R, Smith C, Norris MD.
J Pediatr. 2019 Sep;212:73-78. doi: 10.1016/j.jpeds.2019.04.060. Epub 2019 Jun 8.
PMID: 31182220
Select item 31329926
Ko JM, White KS, Kovacs AH, Tecson KM, Apers S, Luyckx K, Thomet C, Budts W, Enomoto J, Sluman MA, Wang JK, Jackson JL, Khairy P, Cook SC, Chidambarathanu S, Alday L, Eriksen K, Dellborg M, Berghammer M, Johansson B, Mackie AS, Menahem S, Caruana M, Veldtman G, Soufi A, Fernandes SM, Callus E, Kutty S, Moons P, Cedars AM; APPROACH-IS consortium and International Society for Adult Congenital Heart Disease (ISACHD).
J Psychosom Res. 2019 Sep;124:109762. doi: 10.1016/j.jpsychores.2019.109762. Epub 2019 Jul 5.
PMID: 31443808
Select item 31026793
Park HK.
Korean Circ J. 2019 Sep;49(9):864-865. doi: 10.4070/kcj.2019.0259. No abstract available.
PMID: 31456377 Free PMC Article
Select item 31165593
Ramchandani BK, Polo L, Sánchez R, Rey J, González Á, Díez J, Aroca Á.
Korean Circ J. 2019 Sep;49(9):856-863. doi: 10.4070/kcj.2019.0015. Epub 2019 May 7.
PMID: 31165593 Free PMC Article
Select item 31582699
Wang W, Feng P, Wang L, Dong Q, Huang W.
Medicine (Baltimore). 2019 Sep;98(36):e17044. doi: 10.1097/MD.0000000000017044.
PMID: 31490396 Free PMC Article
Select item 31393094
Larkin G, Bellomo T, Caze L.
Nursing. 2019 Sep;49(9):24-31. doi: 10.1097/01.NURSE.0000577688.41805.80.
PMID: 31365456
Select item 30484210
Yücel M, Alp H, Yorulmaz A, Karaarslan S, Baysal T.
Turk Kardiyol Dern Ars. 2019 Sep;47(6):466-475. doi: 10.5543/tkda.2019.33558.
PMID: 31483301 Free Article
Select item 30334300
Siegmund AS, Kampman MAM, Oudijk MA, Mulder BJM, Sieswerda GTJ, Koenen SV, Hummel YM, de Laat MWM, Sollie-Szarynska KM, Groen H, van Dijk APJ, van Veldhuisen DJ, Bilardo CM, Pieper PG.
Ultrasound Obstet Gynecol. 2019 Sep;54(3):359-366. doi: 10.1002/uog.20148.
PMID: 30334300
Select item 31496419
Lerner RK, Gruber N, Pollak U.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):604-615. doi: 10.1177/2150135119857704.
PMID: 31496400
Select item 31496399
Correia-Costa A, Granja S.
Cardiol Young. 2019 Sep 24:1-2. doi: 10.1017/S104795111900221X. [Epub ahead of print] No abstract available.
PMID: 31549603
Select item 31537267
Vukomanovic V, Prijic S, Krasic S, Borovic R, Ninic S, Nesic D, Bjelakovic B, Popovic S, Stajević M, Petrović G.
Medicina (Kaunas). 2019 Sep 20;55(10). pii: E609. doi: 10.3390/medicina55100609.
PMID: 31547038 Free Article
Select item 31539915
Holbein CE, Peugh J, Veldtman GR, Apers S, Luyckx K, Kovacs AH, Thomet C, Budts W, Enomoto J, Sluman MA, Lu CW, Jackson JL, Khairy P, Cook SC, Chidambarathanu S, Alday L, Eriksen K, Dellborg M, Berghammer M, Johansson B, Mackie AS, Menahem S, Caruana M, Soufi A, Fernandes SM, White K, Callus E, Kutty S, Moons P; APPROACH-IS consortium and the International Society for Adult Congenital Heart Disease (ISACHD).
Eur J Prev Cardiol. 2019 Sep 17:2047487319876231. doi: 10.1177/2047487319876231. [Epub ahead of print]
PMID: 31529991
Select item 31527676
Akam-Venkata J, Sriram C, French M, Smith R, Aggarwal S.
Pediatr Cardiol. 2019 Sep 17. doi: 10.1007/s00246-019-02205-0. [Epub ahead of print]
PMID: 31529227
Select item 31522698
Egbe AC, Taggart NW, Reddy YNV, Sufian M, Banala K, Vojjini R, Najam M, Osman K, Obokata M, Borlaug BA.
Am J Cardiol. 2019 Sep 9. pii: S0002-9149(19)31003-3. doi: 10.1016/j.amjcard.2019.08.035. [Epub ahead of print]
PMID: 31586531
Select item 31501090
Cabrera-Mino C, Roy B, Woo MA, Singh S, Moye S, Halnon NJ, Lewis AB, Kumar R, Pike NA.
Pediatr Res. 2019 Sep 9. doi: 10.1038/s41390-019-0569-3. [Epub ahead of print]
PMID: 31499515
Select item 31493782
Jhou HJ, Ke LY, Wu JR, Chen YF.
Pediatr Cardiol. 2019 Sep 3. doi: 10.1007/s00246-019-02184-2. [Epub ahead of print]
PMID: 31482238
Select item 31482237
Fouilloux V, Aldebert P, Gorincour G.
Cardiol Young. 2019 Sep;29(9):1206-1207. doi: 10.1017/S1047951119001690. Epub 2019 Aug 22.
PMID: 31434603
Select item 31412970
Li X, Chen N, Zhou X, Yang Y, Chen S, Song Y, Sun K, Du Q.
J Cardiopulm Rehabil Prev. 2019 Sep;39(5):299-307. doi: 10.1097/HCR.0000000000000420.
PMID: 31343584
Select item 31257650
Ait Ali L, Aquaro GD, Peritore G, Ricci F, De Marchi D, Emdin M, Passino C, Festa P.
J Magn Reson Imaging. 2019 Sep;50(3):779-786. doi: 10.1002/jmri.26684. Epub 2019 Mar 5.
PMID: 30838716
Select item 30714251
Nielsen C, Ratiu I, Esfandiarei M, Chen A, Selamet Tierney ES.
J Pediatr Genet. 2019 Sep;8(3):109-122. doi: 10.1055/s-0039-1693663. Epub 2019 Jul 25. Review.
PMID: 31406616
Select item 31404392
Ko JM, White KS, Kovacs AH, Tecson KM, Apers S, Luyckx K, Thomet C, Budts W, Enomoto J, Sluman MA, Wang JK, Jackson JL, Khairy P, Cook SC, Chidambarathanu S, Alday L, Eriksen K, Dellborg M, Berghammer M, Johansson B, Mackie AS, Menahem S, Caruana M, Veldtman G, Soufi A, Fernandes SM, Callus E, Kutty S, Moons P, Cedars AM; APPROACH-IS consortium and International Society for Adult Congenital Heart Disease (ISACHD).
J Psychosom Res. 2019 Sep;124:109762. doi: 10.1016/j.jpsychores.2019.109762. Epub 2019 Jul 5.
PMID: 31443808
Select item 29973131
Rajiah P, MacNamara J, Chaturvedi A, Ashwath R, Fulton NL, Goerne H.
Radiographics. 2019 Sep-Oct;39(5):1238-1263. doi: 10.1148/rg.2019180176. Epub 2019 Aug 2.
PMID: 31373865
Select item 31356765
ACHD Electrophysiology Featured Articles
Congenital and Pediatric Cardiac EP Reviews of September 2019 Manuscripts
Congenital and Pediatric Cardiac EP Reviews of September 2019 Manuscripts
Long term follow-up after ventricular tachycardia ablation in patients with congenital heart disease.
Yang J, Brunnquell M, Liang JJ, Callans DJ, Garcia FC, Lin D, Frankel DS, Kay J, Marchlinski FE, Tzou W, Sauer WH, Liu B, Ruckdeschel ES, Collins K, Santangeli P, Nguyen DT.
J Cardiovasc Electrophysiol. 2019 Sep;30(9):1560-1568. doi: 10.1111/jce.13996. Epub 2019 Jun 11.
PMID: 31111602
Select item 31115957
Take-Home Points:
- This was a large two-center study of CHD VT ablation with 5-year follow up data.
- The mechanism of VT in congenital heart disease was primarily scar-related reentry (80%), followed by focal (15%) and non-scar related reentry (5%).
- Scar-related reentry was more commonly seen among patients with TOF vs other CHD anatomies.
- Acute complete procedural success could be achieved in 75% of patients overall, with recurrence in 20% of patients.
- Acute procedural success was strongly associated with ventricular arrhythmia-free survival.
Commentary by Dr. Jeremy Moore (Los Angeles) Congenital and Pediatric Cardiac EP section editor: This was a retrospective two-center study of VT catheter ablation outcomes over a 7-year period from 2010 to 2017. Forty-eight patients with variable CHD anatomy were identified, most commonly TOF in 29 (60%), Ebstein’s anomaly in 4 (8%), and bicuspid aortic valve in 4 (8%). Approximately three-quarters had an ICD in place and half had failed antiarrhythmic drugs. Overall, 77 unique VTs were induced, of which approximately half (52%) were hemodynamically stable and could be localized with activation or entrainment mapping. The remainder were identified by pace mapping. The mechanism was scar-related reentry in 81%, non-scar (His-Purkinje)-related reentry in 16%, and focal (mainly outflow tract in 73%) in the remaining 4%. His-Purkinje reentry (4) was seen only observed among patients with Ebstein’s anomaly (2) and TOF (2). Interestingly, the authors noted that VT CL was shorter for patients with preserved RV function versus RV dysfunction (286 ± 7 ms vs 322 ± 18 ms; P = .0246). In addition, TOF patients were more likely to manifest scar-related reentry.
Acute success was achieved in 75% of patients, with recurrent VT in 21% over nearly 5-year follow up. Patients with acute success were less likely to experience recurrent VT (17% vs. 54%, p=0.02). Five of 10 patients with recurrence were taken for a second catheter ablation procedure. In 1 patient, the same anatomical isthmus was targeted; and in 2 others, a separate site was targeted (right coronary cusp in 1 and RBB in 1). The final 2 patients had no inducible VT at repeat catheter ablation and substrate-based ablation was pursued. There were no major complications from catheter ablation. At last follow up, only 8 patients remained on antiarrhythmic drugs.
This study is notable as it is the largest series to date, describing catheter ablation outcomes in mixed CHD cohort with VT. The acute efficacy of 75% with no major complications suggest that this approach is a very reasonable therapeutic modality for affected patients. Similar to a smaller prior description from the Mayo Clinic [Martin et al. Heart Rhythm 2016;13:1449-1454), mechanisms were predominantly scar-related and anatomically based, with a significant number of focal VTs. Although reassuring, the issue of catheter ablation as a substitute for ICD placement was not fully resolved from this interesting experience.
CHD EP Sept 2019
Massey SL, Abend NS, Gaynor JW, Licht DJ, Nadkarni VM, Topjian AA, Xiao R, Naim MY.
Resuscitation. 2019 Sep 24;144:67-74. doi: 10.1016/j.resuscitation.2019.09.005. [Epub ahead of print]
PMID: 31560988
Select item 31582282
Pranata R, Tondas AE, Yonas E, Chintya V, Yamin M.
Indian Pacing Electrophysiol J. 2019 Sep 18. pii: S0972-6292(19)30116-0. doi: 10.1016/j.ipej.2019.09.005. [Epub ahead of print]
PMID: 31541679 Free Article
Select item 31533759
van der Werf C, Lieve KV, Bos JM, Lane CM, Denjoy I, Roses-Noguer F, Aiba T, Wada Y, Ingles J, Leren IS, Rudic B, Schwartz PJ, Maltret A, Sacher F, Skinner JR, Krahn AD, Roston TM, Tfelt-Hansen J, Swan H, Robyns T, Ohno S, Roberts JD, van den Berg MP, Kammeraad JA, Probst V, Kannankeril PJ, Blom NA, Behr ER, Borggrefe M, Haugaa KH, Semsarian C, Horie M, Shimizu W, Till JA, Leenhardt A, Ackerman MJ, Wilde AA.
Eur Heart J. 2019 Sep 14;40(35):2953-2961. doi: 10.1093/eurheartj/ehz309.
PMID: 31145795
Select item 31522246
Miyazaki A, Yoshimura SI, Matsutani H, Miyake M, Negishi J, Yamanaka K, Yamada O, Doi H, Ohuchi H.
Cardiol Young. 2019 Sep 11:1-5. doi: 10.1017/S1047951119002257. [Epub ahead of print]
PMID: 31507257
Select item 31508848
Tseng WC, Wu MH, Lu CW, Wu KL, Wang JK, Lin MT, Chen CA, Chiu SN.
Acta Cardiol Sin. 2019 Sep;35(5):476-483. doi: 10.6515/ACS.201909_35(5).20190211A.
PMID: 31571796 Free PMC Article
Select item 31299559
Saxena A, Relan J, Agarwal R, Awasthy N, Azad S, Chakrabarty M, Dagar KS, Devagourou V, Dharan BS, Gupta SK, Iyer KS, Jayranganath M, Joshi R, Kannan B, Katewa A, Kohli V, Kothari SS, Krishnamoorthy KM, Kulkarni S, Kumar RM, Kumar RK, Maheshwari S, Manohar K, Marwah A, Mishra S, Mohanty SR, Murthy KS, Rao KN, Suresh PV, Radhakrishnan S, Rajashekar P, Ramakrishnan S, Rao N, Rao SG, Chinnaswamy Reddy HM, Sharma R, Shivaprakash K, Subramanyan R, Kumar RS, Talwar S, Tomar M, Verma S, Vijaykumar R.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):254-286. doi: 10.4103/apc.APC_32_19.
PMID: 31516283 Free PMC Article
Select item 31516281
Guarguagli S, Kempny A, Cazzoli I, Barracano R, Gatzoulis MA, Dimopoulos K, Ernst S.
Europace. 2019 Sep 1;21(9):1334-1344. doi: 10.1093/europace/euz157.
PMID: 31168581
Select item 31004150
Gonzalez Corcia MC, Walsh EP, Emani S.
Europace. 2019 Sep 1;21(9):1345-1352. doi: 10.1093/europace/euz056.
PMID: 31004150
Select item 31432698
Creo A, Anderson H, Cannon B, Lteif A, Kumar S, Tebben P, Iqbal AM, Ramakrishna A, Pittock S.
Heart Rhythm. 2019 Sep;16(9):1436-1442. doi: 10.1016/j.hrthm.2019.03.015. Epub 2019 Mar 21.
PMID: 30904484
Select item 30412778
Writing Committee Members, Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD.
Heart Rhythm. 2019 Sep;16(9):e128-e226. doi: 10.1016/j.hrthm.2018.10.037. Epub 2018 Nov 6. No abstract available.
PMID: 30412778
Select item 30412777
Writing Committee Members, Kusumoto FM, Schoenfeld MH, Barrett C, Edgerton JR, Ellenbogen KA, Gold MR, Goldschlager NF, Hamilton RM, Joglar JA, Kim RJ, Lee R, Marine JE, McLeod CJ, Oken KR, Patton KK, Pellegrini CN, Selzman KA, Thompson A, Varosy PD.
Heart Rhythm. 2019 Sep;16(9):e227-e279. doi: 10.1016/j.hrthm.2018.10.036. Epub 2018 Nov 6. No abstract available.
PMID: 30412777
Select item 31263905
Braver O, Semyonov M, Reina Y, Konstantino Y, Haim M, Winter J.
J Cardiothorac Vasc Anesth. 2019 Sep;33(9):2513-2516. doi: 10.1053/j.jvca.2019.04.024. Epub 2019 Apr 26. No abstract available.
PMID: 31130315
Select item 31072707
Shun-Shin MJ, Miyazawa AA, Keene D, Sterliński M, Sokal A, Van Heuverswyn F, Rinaldi CA, Cornelussen R, Stegemann B, Francis DP, Whinnett Z.
J Cardiovasc Electrophysiol. 2019 Sep;30(9):1610-1619. doi: 10.1111/jce.14001. Epub 2019 Jun 25.
PMID: 31115945
Select item 31111602
Yang J, Brunnquell M, Liang JJ, Callans DJ, Garcia FC, Lin D, Frankel DS, Kay J, Marchlinski FE, Tzou W, Sauer WH, Liu B, Ruckdeschel ES, Collins K, Santangeli P, Nguyen DT.
J Cardiovasc Electrophysiol. 2019 Sep;30(9):1560-1568. doi: 10.1111/jce.13996. Epub 2019 Jun 11.
PMID: 31111602
Select item 31115957
Kline J, Costantini O.
Med Clin North Am. 2019 Sep;103(5):945-956. doi: 10.1016/j.mcna.2019.04.007. Review.
PMID: 31378336
Select item 31378327
Kline J, Costantini O.
Med Clin North Am. 2019 Sep;103(5):809-820. doi: 10.1016/j.mcna.2019.05.001. Review.
PMID: 31378327
Select item 31568005
Sekine M, Masutani S, Imamura T, Iwamoto Y, Muraji S, Yoshiba S, Ishido H, Sumitomo N.
Int Heart J. 2019 Sep 27;60(5):1201-1205. doi: 10.1536/ihj.18-723. Epub 2019 Sep 4.
PMID: 31484869 Free Article
Select item 31560378
Oliveira S, Marques B, Laranjo S, Lopes L.
Pediatr Rep. 2019 Sep 24;11(3):8166. doi: 10.4081/pr.2019.8166. eCollection 2019 Sep 24.
PMID: 31579213 Free PMC Article
Select item 31568274
Holmberg MJ, Wiberg S, Ross CE, Kleinman M, Hoeyer-Nielsen AK, Donnino MW, Andersen LW; American Heart Association’s Get With The Guidelines®-Resuscitation Investigators.
Circulation. 2019 Sep 23. doi: 10.1161/CIRCULATIONAHA.119.041667. [Epub ahead of print]
PMID: 31542952
Select item 31545019
Srinivasan C, Balaji S.
Indian Pacing Electrophysiol J. 2019 Sep 18. pii: S0972-6292(19)30115-9. doi: 10.1016/j.ipej.2019.09.004. [Epub ahead of print]
PMID: 31541680 Free Article
Select item 31540546
Bennett JS, Bernhardt M, McBride KL, Reshmi SC, Zmuda E, Kertesz NJ, Garg V, Fitzgerald-Butt S, Kamp AN.
Pediatr Cardiol. 2019 Sep 18. doi: 10.1007/s00246-019-02203-2. [Epub ahead of print]
PMID: 31535183
Select item 31535182
Crotti L, Spazzolini C, Tester DJ, Ghidoni A, Baruteau AE, Beckmann BM, Behr ER, Bennett JS, Bezzina CR, Bhuiyan ZA, Celiker A, Cerrone M, Dagradi F, De Ferrari GM, Etheridge SP, Fatah M, Garcia-Pavia P, Al-Ghamdi S, Hamilton RM, Al-Hassnan ZN, Horie M, Jimenez-Jaimez J, Kanter RJ, Kaski JP, Kotta MC, Lahrouchi N, Makita N, Norrish G, Odland HH, Ohno S, Papagiannis J, Parati G, Sekarski N, Tveten K, Vatta M, Webster G, Wilde AAM, Wojciak J, George AL, Ackerman MJ, Schwartz PJ.
Eur Heart J. 2019 Sep 14;40(35):2964-2975. doi: 10.1093/eurheartj/ehz311.
PMID: 31170290
Select item 31145795
Kim JJ.
Heart Rhythm. 2019 Sep 14. pii: S1547-5271(19)30836-7. doi: 10.1016/j.hrthm.2019.09.015. [Epub ahead of print] No abstract available.
PMID: 31526823
Select item 31522246
Miyazaki A, Yoshimura SI, Matsutani H, Miyake M, Negishi J, Yamanaka K, Yamada O, Doi H, Ohuchi H.
Cardiol Young. 2019 Sep 11:1-5. doi: 10.1017/S1047951119002257. [Epub ahead of print]
PMID: 31507257
Select item 31508849
Voskoboinik A, Hsia H, Moss J, Vedantham V, Tanel RE, Patel A, Wojciak J, Downs N, Scheinman MM.
Heart Rhythm. 2019 Sep 12. pii: S1547-5271(19)30834-3. doi: 10.1016/j.hrthm.2019.09.013. [Epub ahead of print]
PMID: 31521808
Select item 31515886
Ali H, Foresti S, Mariucci E, Bronzetti G, De Ambroggi G, Cappato R.
J Cardiovasc Electrophysiol. 2019 Sep 12. doi: 10.1111/jce.14173. [Epub ahead of print] No abstract available.
PMID: 31515886
Select item 31515865
Cuneo BF, Kaizer AM, Ann Clur S, Swan H, Herberg U, Winbo A, Rydberg A, Haugaa K, Etheridge S, Ackerman MJ, Dagradi F, Killen SAS, Waker-Gussmann A, Benson DW, Wilde AAM, Pan Z, Lam A, Spazzolini C, Horigome H, Schwartz PJ; Fetal LQTS Consortium.
Am J Obstet Gynecol. 2019 Sep 11. pii: S0002-9378(19)31109-3. doi: 10.1016/j.ajog.2019.09.004. [Epub ahead of print]
PMID: 31520628
Select item 31507257
Kim HJ, Kim BG, Park JE, Ki CS, Huh J, Youm JB, Kang JS, Cho H.
Sci Rep. 2019 Sep 10;9(1):12997. doi: 10.1038/s41598-019-49450-0.
PMID: 31506521 Free PMC Article
Select item 31506459
Li Q, Guo R, Gao L, Cui L, Zhao Z, Yu X, Yuan Y, Xu X.
Mol Genet Genomic Med. 2019 Sep 3:e949. doi: 10.1002/mgg3.949. [Epub ahead of print]
PMID: 31482657 Free Article
Select item 31482238
Li ZL, Zeng SY, Liang DP, Liu T, Wang SS, Zhang ZW.
Zhonghua Er Ke Za Zhi. 2019 Sep 2;57(9):700-704. doi: 10.3760/cma.j.issn.0578-1310.2019.09.010. Chinese.
PMID: 31530356
Select item 31571798
Li HY, Chang SL, Chuang CH, Lin MC, Lin YJ, Lo LW, Hu YF, Chung FP, Chang YT, Chung CM, Chen SA, Lee PC.
Acta Cardiol Sin. 2019 Sep;35(5):493-500. doi: 10.6515/ACS.201909_35(5).20190312A.
PMID: 31571798 Free PMC Article
Select item 31301121
Batra AS, Watson R, McCanta AC.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):292-294. doi: 10.4103/apc.APC_131_18.
PMID: 31516285 Free PMC Article
Select item 31516282
Ladas TP, Sugrue A, Nan J, Vaidya VR, Padmanabhan D, Venkatachalam KL, Asirvatham SJ.
Card Electrophysiol Clin. 2019 Sep;11(3):433-448. doi: 10.1016/j.ccep.2019.05.005. Review.
PMID: 31400868
Select item 31400867
Nan J, Sugrue A, Ladas TP, Mehra N, Asirvatham SJ.
Card Electrophysiol Clin. 2019 Sep;11(3):421-432. doi: 10.1016/j.ccep.2019.04.003. Review.
PMID: 31400867
Select item 31451130
Nazer B, Walters TE, Dewland TA, Naniwadekar A, Koruth JS, Najeeb Osman M, Intini A, Chen M, Biermann J, Steinfurt J, Kalman JM, Tanel RE, Lee BK, Badhwar N, Gerstenfeld EP, Scheinman MM.
Circ Arrhythm Electrophysiol. 2019 Sep;12(9):e007337. doi: 10.1161/CIRCEP.119.007337. Epub 2019 Sep 11.
PMID: 31505948
Select item 31500449
Gonzalez Corcia MC, Walsh EP, Emani S.
Europace. 2019 Sep 1;21(9):1345-1352. doi: 10.1093/europace/euz056.
PMID: 31004150
Select item 31432698
Rijnberg FM, Blom NA, Sojak V, Bruggemans EF, Kuipers IM, Rammeloo LAJ, Jongbloed MRM, Bouma BJ, Hazekamp MG.
Interact Cardiovasc Thorac Surg. 2019 Sep 1;29(3):461-468. doi: 10.1093/icvts/ivz111.
PMID: 31038168
Select item 31230902
Chung FP, Vicera JJB, Lin YJ, Chang SL, Lo LW, Hu YF, Lin CY, Tuan TC, Chao TF, Liao JN, Chang TY, Salim S, Liu CM, Chuang CM, Chen CC, Chin CG, Wu CI, Chou CY, Chen SA.
J Cardiovasc Electrophysiol. 2019 Sep;30(9):1508-1516. doi: 10.1111/jce.14057. Epub 2019 Jul 18.
PMID: 31257650
Select item 30776775
Anderson HN, Bos JM, Rohatgi RK, Ackerman MJ.
JACC Clin Electrophysiol. 2019 Sep;5(9):1084-1090. doi: 10.1016/j.jacep.2019.06.008.
PMID: 31537339
Select item 31301000
Paech C, Moser J, Dähnert I, Wagner F, Gebauer RA, Kirsten T, Vogel M, Kiess W, Körner A, Wolfarth B, Wüstenfeld J.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):201-205. doi: 10.4103/apc.APC_90_18.
PMID: 31516275 Free PMC Article
Select item 31516274
ACHD Interventional Cardiology Featured Articles
CHD Interventions September 2019
Interventional Cardiology Reviews of September 2019 Manuscripts
Drug-Eluting Stents Compared With Bare Metal Stents for Stenting the Ductus Arteriosus in Infants With Ductal-Dependent Pulmonary Blood Flow.
Aggarwal V, Dhillon GS, Penny DJ, Gowda ST, Qureshi AM.
Am J Cardiol. 2019 Sep 15;124(6):952-959. doi: 10.1016/j.amjcard.2019.06.014. Epub 2019 Jun 26.
PMID: 31350000
Take-Home Points:
- Drug eluting coronary artery stents (DES) have been theorized to have a lower incidence of neo-intimal proliferation (compared with bare metal stents) when implanted in the ductus arteriosus.
- DES were found to have significantly less luminal loss and fewer unplanned interventions when compared to BMS.
Commentary from Dr. Konstantin Averin (Edmonton, Canada), catheterization section editor of Pediatric Cardiology Journal Watch: Stenting of the ductus arteriosus (DA) is rapidly emerging as an equivalent (or superior) option for augmenting pulmonary blood flow in infants with ductal-dependent pulmonary blood flow (PBF). Drug eluting coronary artery stents (DES) have been theorized to have a lower incidence of neo-intimal proliferation but data comparing them to bare metal stents (BMS) in this patient population are lacking. The authors sought to compare the safety and efficacy of DES to BMS in neonates undergoing DA stenting for ductal-dependent PBF.
Over a 14 year period (2004-2018) 71 infants with confluent central pulmonary arteries underwent ductal stenting for ductal-dependent PBF (46 BMS and 25 DES) with stent selection being uniform during the study period. The baseline characteristics of the cohort as a whole were unremarkable and were similar between the 2 groups (BMS v DES). Freedom from ≥ 50% luminal loss was significantly higher in the DES group (see Kaplan Meier curve below) with the odds ratio for a 50% loss in luminal diameter (as assessed via a subsequent angiographic evaluation) being 1.6 (95% CI 1.2-2.3) for BMS v DES. Sixteen infants (23%) underwent unplanned re-interventions to treat cyanosis, with a significantly higher percentage in the BMS group (28%) compared to the DES group (12%), p=0.02.
There was no mortality difference between the groups. Given concerns about serum drug levels in infants with DES, the authors compared rates of infection between the 2 groups and found the rate of bacterial infection to be higher in the DES group (8% v 2%) but this did not reach statistical significance.
The authors conclude that luminal loss was significantly less and unplanned interventions less common in patients with DES compared to BMS. While the authors did not measure serum drug levels, even if they had been elevated there do not appear to have been significant clinical sequela related to this (consistent with prior reports). Intuition would suggest that anti-proliferative agents would mitigate neo-intimal proliferation of ductal tissue and this report begins to lend credence to that theory. Given the data presented in this report, providers should strongly consider use of DES (vs BMS) for ductal stenting.
CHD Interventions Sept 2019
Kern MC, Janardhanan R, Kelly T, Fox KA, Klewer SE, Seckeler MD.
J Cardiovasc Comput Tomogr. 2019 Sep 29. pii: S1934-5925(19)30450-2. doi: 10.1016/j.jcct.2019.09.018. [Epub ahead of print] No abstract available.
PMID: 31587967
Select item 31568748
Khambadkone S, Burch M, Fenton M, Derrick G, Thiruchelvam T, Karimova A, Bohuta L, Hsia TY.
Ann Thorac Surg. 2019 Sep 27. pii: S0003-4975(19)31434-1. doi: 10.1016/j.athoracsur.2019.08.044. [Epub ahead of print]
PMID: 31568748
Select item 31568860
Schmiady MO, Greutmann M, Pfiffner R, Rancic Z.
Eur Heart J. 2019 Sep 21;40(36):3065. doi: 10.1093/eurheartj/ehz053. No abstract available.
PMID: 30805620
Select item 31326119
Lau IWW, Sun Z.
J Clin Med. 2019 Sep 18;8(9). pii: E1483. doi: 10.3390/jcm8091483. Review.
PMID: 31540421 Free Article
Select item 31532867
Sueda S, Kohno H.
Heart Vessels. 2019 Sep 16. doi: 10.1007/s00380-019-01507-w. [Epub ahead of print]
PMID: 31529177
Select item 31158496
Shi D, Kang Y, Zhang G, Gao C, Lu W, Zou H, Jiang H.
Acta Biomater. 2019 Sep 15;96:68-80. doi: 10.1016/j.actbio.2019.05.073. Epub 2019 May 31. Review.
PMID: 31158496
Select item 31327487
Wang S, Pan J, Xiao B, Tang Y, Lan J, Zheng X, Yang C, Xu D, Zhang J.
Congenit Heart Dis. 2019 Sep 12. doi: 10.1111/chd.12844. [Epub ahead of print]
PMID: 31513356
Select item 31513339
Kops SA, Pangburn S, Barber BJ, Seckeler MD.
Catheter Cardiovasc Interv. 2019 Sep 5. doi: 10.1002/ccd.28489. [Epub ahead of print]
PMID: 31486566
Select item 31348032
Yoldaş T, Örün UA.
Pediatr Cardiol. 2019 Sep 4. doi: 10.1007/s00246-019-02198-w. [Epub ahead of print]
PMID: 31485699
Select item 31492537
Kalfa D, Torres AJ.
Arch Cardiovasc Dis. 2019 Sep 3. pii: S1875-2136(19)30136-6. doi: 10.1016/j.acvd.2019.06.006. [Epub ahead of print] Review.
PMID: 31492537
Select item 31564989
Rigatelli G, Nghia NT, Zuin M, Conte L, D’Elia K, Nanjundappa A.
Clin Radiol. 2019 Sep;74(9):732.e17-732.e22. doi: 10.1016/j.crad.2019.05.017. Epub 2019 Jun 20.
PMID: 31230756
Select item 30315601
Lehner A, Dashkalova T, Ulrich S, Fernandez Rodriguez S, Mandilaras G, Jakob A, Dalla-Pozza R, Fischer M, Schneider H, Tarusinov G, Kampmann C, Hofbeck M, Dähnert I, Kanaan M, Haas NA.
Expert Rev Med Devices. 2019 Sep;16(9):829-834. doi: 10.1080/17434440.2019.1653180. Epub 2019 Aug 30.
PMID: 31432698
Select item 31386585
Hang D, Miller RE, Rokkas CK, Pagel PS.
J Cardiothorac Vasc Anesth. 2019 Sep;33(9):2600-2603. doi: 10.1053/j.jvca.2019.03.028. Epub 2019 Mar 16. No abstract available.
PMID: 31072707
Select item 31115945
Miller JR, Eghtesady P.
J Thorac Cardiovasc Surg. 2019 Sep;158(3):851-852. doi: 10.1016/j.jtcvs.2019.05.041. Epub 2019 May 30. No abstract available.
PMID: 31277816
Select item 31235351
Pascual-Tejerina V, Sánchez-Recalde Á, Gutiérrez-Larraya F, Zamorano JL.
JACC Cardiovasc Interv. 2019 Sep 23;12(18):e159-e160. doi: 10.1016/j.jcin.2019.06.016. Epub 2019 Aug 28. No abstract available.
PMID: 31473233
Select item 31549187
Taha F, Elshedoudy S.
Echocardiography. 2019 Sep 21. doi: 10.1111/echo.14482. [Epub ahead of print]
PMID: 31541598
Select item 31548437
van den Berg G, Helbing WA, van Beynum I, Krasemann TB.
Pediatr Cardiol. 2019 Sep 18. doi: 10.1007/s00246-019-02211-2. [Epub ahead of print]
PMID: 31535182
Select item 31568240
Aggarwal V, Dhillon GS, Penny DJ, Gowda ST, Qureshi AM.
Am J Cardiol. 2019 Sep 15;124(6):952-959. doi: 10.1016/j.amjcard.2019.06.014. Epub 2019 Jun 26.
PMID: 31350000
Select item 31327487
Bradley EA, Ammash N, Martinez SC, Chin K, Hebson C, Singh HS, Aboulhosn J, Grewal J, Billadello J, Chakinala MM, Daniels CJ, Zaidi AN.
Int J Cardiol. 2019 Sep 15;291:127-133. doi: 10.1016/j.ijcard.2019.03.056. Epub 2019 Apr 17.
PMID: 31031077
Select item 30952528
Bebawy CM, Gordon BM, Bock MJ.
Cardiol Young. 2019 Sep 13:1-3. doi: 10.1017/S1047951119002130. [Epub ahead of print]
PMID: 31514756
Select item 31520151
Jhaveri S, Prieto L, Suntharos P.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):342-344. doi: 10.4103/apc.APC_143_18.
PMID: 31516300 Free PMC Article
Select item 31516299
Perez-Brandão C, Fiarresga A, Sousa L, Martins JD.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):329-332. doi: 10.4103/apc.APC_175_18.
PMID: 31516296 Free PMC Article
Select item 31516295
Hussain I, KhawajaKhail R, Khattak K, Irfan M, Gul AM.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):321-324. doi: 10.4103/apc.APC_155_18.
PMID: 31516294 Free PMC Article
Select item 31516291
Barnes JH, Boesch RP, Balakrishnan K, Said SM, Van Dorn CS.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):308-311. doi: 10.4103/apc.APC_94_18.
PMID: 31516290 Free PMC Article
Select item 31516288
Maksymenko AV, Kuzmenko YL, Dovhaliuk AA, Motrechko OO, Herrmann FE, Haas NA, Lehner A.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):206-211. doi: 10.4103/apc.APC_151_18.
PMID: 31516276 Free PMC Article
Select item 31516275
Osula D, Farris GR, Chatterjee A, Law MA, Cribbs MG.
Circ Heart Fail. 2019 Sep;12(9):e006130. doi: 10.1161/CIRCHEARTFAILURE.119.006130. Epub 2019 Sep 2. No abstract available.
PMID: 31474118
Select item 31020475
Haas NA, Vcasna R, Laser KT, Blanz U, Herrmann FE, Jakob A, Fischer M, Kanaan M, Lehner A.
J Cardiol. 2019 Sep;74(3):217-222. doi: 10.1016/j.jjcc.2019.03.021. Epub 2019 Jun 21.
PMID: 31230902
Select item 31113702
Lehner A, Haas NA, Dietl M, Jakob A, Schulze-Neick I, Dalla Pozza R, Rodriguez SF, Fischer M.
J Cardiol. 2019 Sep;74(3):197-205. doi: 10.1016/j.jjcc.2019.04.007. Epub 2019 May 18. Review.
PMID: 31113702
Select item 31343584
Michalak KW, Wernovsky G, Moll M, Anderson RH.
J Thorac Cardiovasc Surg. 2019 Sep;158(3):e107-e109. doi: 10.1016/j.jtcvs.2019.03.087. Epub 2019 Apr 4. No abstract available.
PMID: 31036358
Select item 30982585
Epçaçan S, Bulut MO, Kaya Y, Yücel IK, Çakır Ç, Şişli E, Ceylan Y, Çelebi A.
Turk Kardiyol Dern Ars. 2019 Sep;47(6):431-439. doi: 10.5543/tkda.2019.20805.
PMID: 31483299 Free Article
Select item 30338597
Palacios-Macedo A, Díliz-Nava H, Tamariz-Cruz O, García-Benítez L, Pérez-Juárez F, Araujo-Martínez A, Mier-Martínez M, Corona-Villalobos C, Castañuela V, March A, López-Terrazas J, Cabrera AG.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):590-596. doi: 10.1177/2150135119862607.
PMID: 31496420
Select item 31496415
Menaissy Y, Alkady H, El-Saiedi S.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):539-542. doi: 10.1177/2150135119852318.
PMID: 31496402
Select item 31496401
Sengun B, Yıldırım I, Yıldız Ö, Çeliker A.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):312-314. doi: 10.4103/apc.APC_162_18.
PMID: 31516291 Free PMC Article
Select item 31516290
ACHD Surgery
Congenital Heart Surgery Reviews of September 2019 Manuscripts
CHD Surgery Sept 2019
Right Ventricle Dependent Coronary Circulation: Location of Obstruction is Associated with Survival.
Spigel Z, Qureshi AM, Morris SA, Mery CM, Sexson-Tejtel SK, Zea-Vera R, Binsalamah Z, Imamura M, Heinle J, Adachi I.
Ann Thorac Surg. 2019 Sep 30. pii: S0003-4975(19)31457-2. doi: 10.1016/j.athoracsur.2019.08.066. [Epub ahead of print]
PMID: 31580859
Select item 31580857
Li Q, Hara H, Banks CA, Yamamoto T, Ayares D, Mauchley DC, Dabal RJ, Padilla L, Carlo WF, Rhodes LA, Cooper DKC, Cleveland DC.
Ann Thorac Surg. 2019 Sep 30. pii: S0003-4975(19)31452-3. doi: 10.1016/j.athoracsur.2019.08.061. [Epub ahead of print]
PMID: 31580857
Select item 31568572
Polivenok I, Gelatt M, Cardarelli M.
Curr Opin Cardiol. 2019 Sep 30. doi: 10.1097/HCO.0000000000000691. [Epub ahead of print]
PMID: 31574003
Select item 31570783
Binsalamah ZM, Spigel ZA, Zhu H, Kim MB, Chacon-Portillo MA, Adachi I, Imamura M, Mery CM, Mckenzie ED, Fraser CD, Heinle JS.
Cardiol Young. 2019 Sep 26:1-6. doi: 10.1017/S1047951119002336. [Epub ahead of print]
PMID: 31554530
Select item 31554525
Peng B, Wang Q.
J Int Med Res. 2019 Sep 26:300060518818021. doi: 10.1177/0300060518818021. [Epub ahead of print] No abstract available.
PMID: 31558080
Select item 31568238
Sochet AA, Grindy AK, Son S, Barrie EK, Hickok RL, Nakagawa TA, Wilsey MJ.
Pediatr Crit Care Med. 2019 Sep 26. doi: 10.1097/PCC.0000000000002129. [Epub ahead of print]
PMID: 31568238
Select item 31567409
Malik G, Pidborochynski T, Buchholz H, Freed DH, Al-Aklabi M, Bozso SJ, Choudhry S, Anand V, Holinski P, Conway J.
ASAIO J. 2019 Sep 25. doi: 10.1097/MAT.0000000000001078. [Epub ahead of print]
PMID: 31567409
Select item 31563274
Savla JJ, Faerber JA, Huang YV, Zaoutis T, Goldmuntz E, Kawut SM, Mercer-Rosa L.
J Am Coll Cardiol. 2019 Sep 24;74(12):1570-1579. doi: 10.1016/j.jacc.2019.05.057.
PMID: 31537267
Select item 31561958
Fakhri D, Marwali EM, Budiwardhana N, Roebiono PS, Rahajoe AU, Caesario M.
Asian Cardiovasc Thorac Ann. 2019 Sep 23:218492319879529. doi: 10.1177/0218492319879529. [Epub ahead of print] No abstract available.
PMID: 31547669
Select item 31548181
Bobillo-Perez S, Sanchez-de-Toledo J, Segura S, Girona-Alarcon M, Mele M, Sole-Ribalta A, Cañizo Vazquez D, Jordan I, Cambra FJ.
Congenit Heart Dis. 2019 Sep 23. doi: 10.1111/chd.12846. [Epub ahead of print]
PMID: 31545015
Select item 31549332
Fan C, Tang M, Wu S, Yuan S, Borovjagin AV, Yang J.
Pediatr Cardiol. 2019 Sep 23. doi: 10.1007/s00246-019-02212-1. [Epub ahead of print]
PMID: 31549187
Select item 31549230
Magnetta DA, Godown J, West S, Zinn M, Rose-Felker K, Miller S, Feingold B.
Am J Transplant. 2019 Sep 22. doi: 10.1111/ajt.15567. [Epub ahead of print]
PMID: 31544351
Select item 30805620
Liekiene D, Bezuska L, Semeniene P, Cypiene R, Lebetkevicius V, Tarutis V, Barysiene J, Rucinskas K, Sirvydis V.
Medicina (Kaunas). 2019 Sep 19;55(9). pii: E608. doi: 10.3390/medicina55090608.
PMID: 31546957 Free Article
Select item 31537853
Ganigara M, Doshi A, Naimi I, Mahadevaiah GP, Buddhe S, Chikkabyrappa SM.
Semin Cardiothorac Vasc Anesth. 2019 Sep 19:1089253219873004. doi: 10.1177/1089253219873004. [Epub ahead of print]
PMID: 31535945
Select item 31541634
Alsalehi M, Jeewa A, Wan A, Contreras J, Yoo SJ, Laks JA.
Congenit Heart Dis. 2019 Sep 18. doi: 10.1111/chd.12842. [Epub ahead of print] Review.
PMID: 31532081
Select item 31534214
Abdel-Bary M, Abdel-Baseer KA, Abdel-Latif AF, Abdel-Naser MA, Nafie M, Eisa KM.
J Cardiothorac Surg. 2019 Sep 18;14(1):168. doi: 10.1186/s13019-019-0990-z.
PMID: 31533759 Free PMC Article
Select item 31540421
Fang A, Allen KY, Marino BS, Brady KM.
Paediatr Anaesth. 2019 Sep 18. doi: 10.1111/pan.13744. [Epub ahead of print]
PMID: 31532867
Select item 31535184
Mao CY, Mahle WT.
Am J Transplant. 2019 Sep 17. doi: 10.1111/ajt.15596. [Epub ahead of print]
PMID: 31529765
Select item 31526142
Michel J, Hofbeck M, Peper AK, Kumpf M, Neunhoeffer F.
Curr Med Res Opin. 2019 Sep 17:1-6. doi: 10.1080/03007995.2019.1663689. [Epub ahead of print]
PMID: 31526142
Select item 31529991
Egbe AC, Miranda WR, Ammash NM, Said SM, Missula VR, Abdelsamid MF, Kothapalli S, Connolly HM.
Int J Cardiol. 2019 Sep 15;291:45-49. doi: 10.1016/j.ijcard.2019.02.028. Epub 2019 Feb 16.
PMID: 30803889
Select item 30772012
Padalino MA, Franchetti N, Sarris GE, Hazekamp M, Carrel T, Frigiola A, Horer J, Roussin R, Cleuziou J, Meyns B, Fragata J, Telles H, Polimenakos AC, Francois K, Veshti A, Salminen J, Rocafort AG, Nosal M, Vedovelli L, Protopapas E, Tumbarello R, Merola A, Pegoraro C, Motta R, Boccuzzo G, Sojak V, Rito ML, Caldaroni F, Corrado D, Basso C, Stellin G.
Int J Cardiol. 2019 Sep 15;291:189-193. doi: 10.1016/j.ijcard.2019.02.007. Epub 2019 Feb 10.
PMID: 30772012 Free Article
Select item 31178488
Kojima T, Toda K, Oyanagi T, Yoshiba S, Kobayashi T, Sumitomo N.
Heart Vessels. 2019 Sep 14. doi: 10.1007/s00380-019-01497-9. [Epub ahead of print]
PMID: 31522246
Select item 31515672
Satriano A, Franchini S, Lapergola G, Pluchinotta F, Anastasia L, Baryshnikova E, Livolti G, Gazzolo D.
Diagnostics (Basel). 2019 Sep 13;9(3). pii: E118. doi: 10.3390/diagnostics9030118.
PMID: 31540197 Free Article
Select item 31514562
Chen F, You Y, Ding P, Wu K, Mo X.
Fetal Pediatr Pathol. 2019 Sep 13:1-8. doi: 10.1080/15513815.2019.1661050. [Epub ahead of print]
PMID: 31514562
Select item 31520462
- Efficacy and safety of dacron patch in surgical treatment of congenital disease by echocardiography.
Deng M, Yang Q.
J Infect Public Health. 2019 Sep 13. pii: S1876-0341(19)30275-8. doi: 10.1016/j.jiph.2019.08.009. [Epub ahead of print]
PMID: 31526640 Free Article
Select item 31521596
Vida VL, Zanotto L, Zanotto L, Triglia LT, Bellanti E, Castaldi B, Padalino MA, Gasperetti A, Battista F, Varnier M, Stellin G.
J Card Surg. 2019 Sep 11. doi: 10.1111/jocs.14045. [Epub ahead of print]
PMID: 31508848
Select item 31521397
Brown KL, Pagel C, Ridout D, Wray J, Anderson D, Barron DJ, Cassidy J, Davis P, Hudson E, Jones A, Mclean A, Morris S, Rodrigues W, Sheehan K, Stoica S, Tibby SM, Witter T, Tsang VT; Cardiac Impact Study Group.
BMJ Open. 2019 Sep 9;9(9):e028533. doi: 10.1136/bmjopen-2018-028533.
PMID: 31501104 Free PMC Article
Select item 31501090
Parikh CR, Greenberg JH, McArthur E, Thiessen-Philbrook H, Everett AD, Wald R, Zappitelli M, Chanchlani R, Garg AX.
Clin J Am Soc Nephrol. 2019 Sep 9. pii: CJN.00690119. doi: 10.2215/CJN.00690119. [Epub ahead of print]
PMID: 31501090
Select item 31498562
Zhou C, Tong Y, Feng Z, Cui Y, Zhao M, Hu J, Liu K, Zhao J, Liu J.
Artif Organs. 2019 Sep 8. doi: 10.1111/aor.13561. [Epub ahead of print]
PMID: 31494945
Select item 31511192
Purifoy ET, Spray BJ, Riley JS, Prodhan P, Bolin EH.
Pediatr Cardiol. 2019 Sep 7. doi: 10.1007/s00246-019-02196-y. [Epub ahead of print]
PMID: 31494702
Select item 31489832
Morrison ML, Grant B, McCrossan BA, Sands AJ, Owens CG, Spence MS, Casey FA, Craig BG, Lockhart CJ.
Congenit Heart Dis. 2019 Sep 6. doi: 10.1111/chd.12822. [Epub ahead of print]
PMID: 31489769
Select item 31492700
Ridderbos FS, Bonenkamp BE, Meyer SL, Eshuis G, Ebels T, van Melle JP, Willems TP, Berger RMF.
Heart. 2019 Sep 6. pii: heartjnl-2019-314972. doi: 10.1136/heartjnl-2019-314972. [Epub ahead of print]
PMID: 31492699
Select item 31517771
Hiraoka A, Tachibana H, Yoshitaka H, Sakaguchi T.
J Card Surg. 2019 Sep 3. doi: 10.1111/jocs.14206. [Epub ahead of print]
PMID: 31478249
Select item 31582201
Pinesi HT, Strabelli TMV, Aiello VD.
Arq Bras Cardiol. 2019 Sep 2;113(2):286-293. doi: 10.5935/abc.20190162. English, Portuguese. No abstract available.
PMID: 31483025 Free Article
Select item 31483331
Oster ME, McCracken C, Kiener A, Aylward B, Cory M, Hunting J, Kochilas LK.
Am J Cardiol. 2019 Sep 1;124(5):795-802. doi: 10.1016/j.amjcard.2019.05.047. Epub 2019 Jun 6.
PMID: 31272703
Select item 31272701
Kadam SV, Tailor KB, Joshi VH, Rao SG.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):351-353. doi: 10.4103/apc.APC_108_18. No abstract available.
PMID: 31516305 Free PMC Article
Select item 31516289
Patil S, Relan J, Hote M, Kothari SS.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):305-307. doi: 10.4103/apc.APC_71_18.
PMID: 31516289 Free PMC Article
Select item 31516284
Talwar S, Siddharth B, Gupta SK, Bhoje A, Choudhary SK.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):287-291. doi: 10.4103/apc.APC_147_18.
PMID: 31516284 Free PMC Article
Select item 31516283
Hartjes TM, Lester D.
Crit Care Nurs Clin North Am. 2019 Sep;31(3):257-265. doi: 10.1016/j.cnc.2019.04.002. Epub 2019 Jun 6. Review.
PMID: 31351549
Select item 31365379
Boethig D, Horke A, Hazekamp M, Meyns B, Rega F, Van Puyvelde J, Hübler M, Schmiady M, Ciubotaru A, Stellin G, Padalino M, Tsang V, Jashari R, Bobylev D, Tudorache I, Cebotari S, Haverich A, Sarikouch S.
Eur J Cardiothorac Surg. 2019 Sep 1;56(3):503-509. doi: 10.1093/ejcts/ezz054.
PMID: 30879050 Free PMC Article
Select item 31297625
Lehnert A, Villemain O, Gaudin R, Méot M, Raisky O, Bonnet D.
Interact Cardiovasc Thorac Surg. 2019 Sep 1;29(3):469-475. doi: 10.1093/icvts/ivz117.
PMID: 31089681
Select item 31374590
Garcia A.
J Card Surg. 2019 Sep;34(9):753. doi: 10.1111/jocs.14178. Epub 2019 Aug 2. No abstract available.
PMID: 31374590
Select item 30928109
Margetson TD, Sleasman J, Kollmann S, McCarthy PJ, Jahadi O, Sheff D, Shuttleworth P, Mainwaring RD, Hanley FL.
J Extra Corpor Technol. 2019 Sep;51(3):147-152.
PMID: 31548736
Select item 30612882
Hsu J, Chang CH, Chiang LT, Caffrey JL, Lin JW, Chen YS.
J Formos Med Assoc. 2019 Sep;118(9):1339-1346. doi: 10.1016/j.jfma.2018.12.008. Epub 2019 Jan 4.
PMID: 30612882 Free Article
Select item 31495407
Lamour JM, Mason KL, Hsu DT, Feingold B, Blume ED, Canter CE, Dipchand AI, Shaddy RE, Mahle WT, Zuckerman WA, Bentlejewski C, Armstrong BD, Morrison Y, Diop H, Iklé DN, Odim J, Zeevi A, Webber SA; CTOTC-04 investigators.
J Heart Lung Transplant. 2019 Sep;38(9):972-981. doi: 10.1016/j.healun.2019.06.006. Epub 2019 Jun 20.
PMID: 31324444
Select item 31317587
Pini Prato A, Arnoldi R, Sgrò A, Felici E, Racca F, Nozza P, Mariani N, Mosconi M, Mazzola C, Mattioli G.
J Pediatr Surg. 2019 Sep;54(9):1838-1842. doi: 10.1016/j.jpedsurg.2019.01.053. Epub 2019 Feb 12.
PMID: 30814038
Select item 30635129
Jegatheeswaran A, Devlin PJ, McCrindle BW, Williams WG, Jacobs ML, Blackstone EH, DeCampli WM, Caldarone CA, Gaynor JW, Kirklin JK, Lorber RO, Mery CM, St Louis JD, Molossi S, Brothers JA.
J Thorac Cardiovasc Surg. 2019 Sep;158(3):822-834.e3. doi: 10.1016/j.jtcvs.2019.02.122. Epub 2019 Mar 28.
PMID: 31235351
Select item 31005300
Tu LN, Timms AE, Kibiryeva N, Bittel D, Pastuszko A, Nigam V, Pastuszko P.
J Thorac Cardiovasc Surg. 2019 Sep;158(3):882-890.e4. doi: 10.1016/j.jtcvs.2019.02.091. Epub 2019 Mar 6.
PMID: 31005300
Select item 30982585
Claessens NHP, Jansen NJG, Breur JMPJ, Algra SO, Stegeman R, Alderliesten T, van Loon K, de Vries LS, Haas F, Benders MJNL, Lemmers PMA.
J Thorac Cardiovasc Surg. 2019 Sep;158(3):867-877.e1. doi: 10.1016/j.jtcvs.2019.02.106. Epub 2019 Mar 14.
PMID: 30982585
Select item 30801451
Marchesotti F, Rondelli V, Pesaresi M, Nicoli S, Vezzosi T, Auriemma E, Lanzillo G, Cuccio A, Khouri T, Dejong A, Domenech O.
J Vet Intern Med. 2019 Sep;33(5):2227-2234. doi: 10.1111/jvim.15580. Epub 2019 Aug 5.
PMID: 31380593 Free PMC Article
Select item 31456377
Nakano T.
Kyobu Geka. 2019 Sep;72(10):799-804. Japanese.
PMID: 31582699
Select item 31582693
Kin H.
Kyobu Geka. 2019 Sep;72(10):767-771. Japanese.
PMID: 31582693
Select item 31506414
Kuwahara Y, Takahashi Y, Wada N.
Kyobu Geka. 2019 Sep;72(9):707-711. Japanese.
PMID: 31506414
Select item 31283925
Yi K, Guo X, You T, Wang Y, Ding F, Hou X, Zhou L.
Medicine (Baltimore). 2019 Sep;98(38):e17270. doi: 10.1097/MD.0000000000017270.
PMID: 31568005 Free Article
Select item 31567953
Bradford TT, Daily JA, Lang SM, Gossett JM, Tang X, Collins RT 2nd.
Pediatr Transplant. 2019 Sep;23(6):e13495. doi: 10.1111/petr.13495. Epub 2019 Jun 6.
PMID: 31169342
Select item 31325555
Futterman C, Salvin JW, McManus M, Lowry AW, Baronov D, Almodovar MC, Pineda JA, Nadkarni VM, Laussen PC, Gazit AZ.
Resuscitation. 2019 Sep;142:74-80. doi: 10.1016/j.resuscitation.2019.07.013. Epub 2019 Jul 17.
PMID: 31325555
Select item 31483301
Schlueter SM, Wilhelm M, Anagnostopoulos PV, Al-Subu AM.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):638-640. doi: 10.1177/2150135119853283.
PMID: 31496419
Select item 31496416
Riggs KW, Kavoosi TA, Kroslowitz B, Zafar F, Heydarian HC, Morales DLS.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):552-557. doi: 10.1177/2150135119860465.
PMID: 31496416
Select item 31496414
Greene CL, Mainwaring RD, Sidell D, Palmon M, Hanley FL.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):558-564. doi: 10.1177/2150135119860466.
PMID: 31496414
Select item 31496410
Vergales J, Seckeler MD, Chew J, Gangemi J.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):599-603. doi: 10.1177/2150135119864575.
PMID: 31496410
Select item 31496407
Rhodes JF Jr, Patel M, Burke RP.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):628-631. doi: 10.1177/2150135119852586.
PMID: 31496407
Select item 31496405
Wijayarathne PM, Skillington P, Menahem S, Thuraisingam A, Larobina M, Grigg L.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):543-551. doi: 10.1177/2150135119859853.
PMID: 31496405
Select item 31496400
Han F, Co-Vu J, Lopez-Colon D, Forder J, Bleiweis M, Reyes K, DeGroff C, Chandran A.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):533-538. doi: 10.1177/2150135119852316.
PMID: 31496399
Riggs KW, Zafar F, Lorts A, Villa CR, Bryant R 3rd, Morales DLS.
ASAIO J. 2019 Sep 30. doi: 10.1097/MAT.0000000000001075. [Epub ahead of print]
PMID: 31577626
Select item 31567418
Bates A, Buchholz H, Freed D, MacArthur R, Pibdorochynski T, Conway J.
ASAIO J. 2019 Sep 30. doi: 10.1097/MAT.0000000000001062. [Epub ahead of print]
PMID: 31567418
Select item 31566150
O’Halloran CP, Thiagarajan RR, Yarlagadda VV, Barbaro RP, Nasr VG, Rycus P, Anders M, Alexander PMA.
Pediatr Crit Care Med. 2019 Sep 27. doi: 10.1097/PCC.0000000000002103. [Epub ahead of print]
PMID: 31567621
Select item 31562687
Godown J, Schumacher KR, Butler A, Chapman G, Dipchand AI, Kaslow WW, Bearl DW, Kirk R.
Pediatr Transplant. 2019 Sep 27:e13589. doi: 10.1111/petr.13589. [Epub ahead of print]
PMID: 31562687
Select item 31554525
Malik G, Pidborochynski T, Buchholz H, Freed DH, Al-Aklabi M, Bozso SJ, Choudhry S, Anand V, Holinski P, Conway J.
ASAIO J. 2019 Sep 25. doi: 10.1097/MAT.0000000000001078. [Epub ahead of print]
PMID: 31567409
Select item 31567407
Savla JJ, Faerber JA, Huang YV, Zaoutis T, Goldmuntz E, Kawut SM, Mercer-Rosa L.
J Am Coll Cardiol. 2019 Sep 24;74(12):1570-1579. doi: 10.1016/j.jacc.2019.05.057.
PMID: 31537267
Select item 31561960
Asimacopoulos EP, Garbern JC, Gauvreau K, Blume ED, Daly KP, Singh TP.
Transplantation. 2019 Sep 24. doi: 10.1097/TP.0000000000002983. [Epub ahead of print]
PMID: 31568274
Select item 31547669
Bobillo-Perez S, Sanchez-de-Toledo J, Segura S, Girona-Alarcon M, Mele M, Sole-Ribalta A, Cañizo Vazquez D, Jordan I, Cambra FJ.
Congenit Heart Dis. 2019 Sep 23. doi: 10.1111/chd.12846. [Epub ahead of print]
PMID: 31545015
Select item 31544560
Deshpande SR, Vaiyani D, Cuadrado AR, McKenzie ED, Maher KO.
Int J Artif Organs. 2019 Sep 23:391398819876940. doi: 10.1177/0391398819876940. [Epub ahead of print]
PMID: 31544560
Select item 31510826
Kojima T, Toda K, Oyanagi T, Yoshiba S, Kobayashi T, Sumitomo N.
Heart Vessels. 2019 Sep 14. doi: 10.1007/s00380-019-01497-9. [Epub ahead of print]
PMID: 31522246
Penk JS, Reddy S, Polito A, Cisco MJ, Allan CK, Bembea M, Giglia TM, Cheng HH, Thiagarajan RR, Dalton HJ.
Pediatr Crit Care Med. 2019 Sep 12. doi: 10.1097/PCC.0000000000002104. [Epub ahead of print]
PMID: 31517728
Select item 31515860
Türköz R, Doğan A, Oktay A, Saygılı A.
J Card Surg. 2019 Sep 11. doi: 10.1111/jocs.14252. [Epub ahead of print]
PMID: 31508849
Select item 31507010
Welke KF, Pasquali SK, Lin P, Backer CL, Overman DM, Romano JC, Karamlou T.
Semin Thorac Cardiovasc Surg. 2019 Sep 10. pii: S1043-0679(19)30274-6. doi: 10.1053/j.semtcvs.2019.09.005. [Epub ahead of print]
PMID: 31518703
Select item 31505063
Parikh CR, Greenberg JH, McArthur E, Thiessen-Philbrook H, Everett AD, Wald R, Zappitelli M, Chanchlani R, Garg AX.
Clin J Am Soc Nephrol. 2019 Sep 9. pii: CJN.00690119. doi: 10.2215/CJN.00690119. [Epub ahead of print]
PMID: 31501090
Select item 31501999
Udi J, Köhler TC, Grohmann J, Bäuml M, Grundmann S, Bode C, Biever P, Duerschmied D.
Clin Res Cardiol. 2019 Sep 9. doi: 10.1007/s00392-019-01544-5. [Epub ahead of print] No abstract available.
PMID: 31501999
Select item 31516692
Purifoy ET, Spray BJ, Riley JS, Prodhan P, Bolin EH.
Pediatr Cardiol. 2019 Sep 7. doi: 10.1007/s00246-019-02196-y. [Epub ahead of print]
PMID: 31494702
Select item 31489778
Mahle WT, Mason KL, Dipchand AI, Richmond M, Feingold B, Canter CE, Hsu DT, Singh TP, Shaddy RE, Armstrong BD, Zeevi A, Iklé DN, Diop H, Odim J, Webber SA; CTOTC-04 Investigators.
Pediatr Transplant. 2019 Sep 4:e13561. doi: 10.1111/petr.13561. [Epub ahead of print]
PMID: 31483086
Select item 31482597
Oh J, Song IK, Cho J, Yun TJ, Park CS, Choi JM, Gwak M, Shin WJ.
Pediatr Cardiol. 2019 Sep 3. doi: 10.1007/s00246-019-02195-z. [Epub ahead of print]
PMID: 31482237
Select item 31482236
Korun O, Yurdakök O, Dedemoğlu M, Yücel İK, Çelebi A, Kudsioğlu ŞT, Sasmazel A, Aydemir NA.
Anatol J Cardiol. 2019 Sep;22(3):125-131. doi: 10.14744/AnatolJCardiol.2019.58235.
PMID: 31475955 Free PMC Article
Select item 31475425
Garekar S, Bharati A, Kothari F, Patil S, Dhake S, Mali S, Mhatre A, Bind D, Joshi A, Soni B, Malankar D.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):295-297. doi: 10.4103/apc.APC_141_18.
PMID: 31516286 Free PMC Article
Select item 31516285
Abushaban L, Uthaman B, Selvan JP, Al Qbandi M, Sharma PN, Mariappa TV.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):212-219. doi: 10.4103/apc.APC_120_18.
PMID: 31516277 Free PMC Article
Select item 31516276
Goldberg JF, Schlosser RS, Walrath JG, Morris SA, Elias BA, Price JF, Cabrera AG, Denfield SW, Dreyer WJ, Wang Y, Adachi I, Jeewa A.
ASAIO J. 2019 Sep/Oct;65(7):725-730. doi: 10.1097/MAT.0000000000000865.
PMID: 30161035
Select item 30754985
Pérez-Andreu J, Fernández-Doblas J, Giralt García G, Roses F, Abella RF.
Asian Cardiovasc Thorac Ann. 2019 Sep;27(7):590-592. doi: 10.1177/0218492318804948. Epub 2019 Feb 12. No abstract available.
PMID: 30754985
Select item 31400868
D’Addese L, Komarlu R, Zahka K.
Cardiol Young. 2019 Sep;29(9):1219-1221. doi: 10.1017/S1047951119001811.
PMID: 31451126
Select item 31434603
Umezu K, Harada Y, Sakamoto T, Okamura T, Shintomi S, Takigiku K, Yasukochi S.
Heart Vessels. 2019 Sep;34(9):1456-1463. doi: 10.1007/s00380-019-01376-3. Epub 2019 Mar 27.
PMID: 30915524
Select item 31122742
Lamour JM, Mason KL, Hsu DT, Feingold B, Blume ED, Canter CE, Dipchand AI, Shaddy RE, Mahle WT, Zuckerman WA, Bentlejewski C, Armstrong BD, Morrison Y, Diop H, Iklé DN, Odim J, Zeevi A, Webber SA; CTOTC-04 investigators.
J Heart Lung Transplant. 2019 Sep;38(9):972-981. doi: 10.1016/j.healun.2019.06.006. Epub 2019 Jun 20.
PMID: 31324444
Select item 31116157
Kumar TKS, Zurakowski D, Briceno-Medina M, Shah A, Sathanandam S, Allen J, Sandhu H, Joshi VM, Boston U, Knott-Craig CJ.
J Thorac Cardiovasc Surg. 2019 Sep;158(3):853-862.e1. doi: 10.1016/j.jtcvs.2019.03.123. Epub 2019 May 11.
PMID: 31204139
Select item 31126642
Karamlou T, Meza JM, Najm HK, Nigro JJ, Hill KD.
J Thorac Cardiovasc Surg. 2019 Sep;158(3):837-842.e5. doi: 10.1016/j.jtcvs.2018.12.121. Epub 2019 Apr 17. No abstract available.
PMID: 31101343
Select item 31036358
Shakoor A, Pedroso FE, Jacobs SE, Okochi S, Zenilman A, Cheung EW, Middlesworth W.
World J Pediatr Congenit Heart Surg. 2019 Sep;10(5):582-589. doi: 10.1177/2150135119862598.
PMID: 31496406
Select item 31496404
Gohain D, Menon S, Baruah SD, Ramanan SV, Dharan BS, Jayakumar K.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):350-351. doi: 10.4103/apc.APC_157_18. No abstract available.
PMID: 31516304 Free PMC Article
Select item 31516303
Riggs KW, Price NM, Szugye N, Goldstein BH, Morales DLS.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):318-320. doi: 10.4103/apc.APC_152_18.
PMID: 31516293 Free PMC Article
Select item 31516292
Patil S, Relan J, Hote M, Kothari SS.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):305-307. doi: 10.4103/apc.APC_71_18.
PMID: 31516289 Free PMC Article
Select item 31516288
Talwar S, Siddharth B, Gupta SK, Bhoje A, Choudhary SK.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):287-291. doi: 10.4103/apc.APC_147_18.
PMID: 31516284 Free PMC Article
Select item 31516283
Vaidyanathan S, Supreet M, Shilpa M, Nelson A, Vijay A.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):228-232. doi: 10.4103/apc.APC_183_18.
PMID: 31516279 Free PMC Article
Select item 3151627
Fetal Cardiology Featured Articles
Fetal Cardiology Reviews of September 2019 Manuscripts
Fetal Cardiology Reviews of September 2019 Manuscripts
Usefulness of Postnatal Echocardiography in Patients with Down Syndrome with Normal Fetal Echocardiograms.
Cooper A, Sisco K, Backes CH, Dutro M, Seabrook R, Santoro SL, Cua CL.
Pediatr Cardiol. 2019 Sep 20. doi: 10.1007/s00246-019-02209-w. [Epub ahead of print]
PMID: 31541264
Select item 31568264
Take-Home Points:
- The incidence of significant congenital heart defects(CHD) on postnatal echocardiograms for patients with Down Syndrome (DS) who had a normal fetal echo is nearly zero.
- Minor CHD, if present, will likely have an abnormal exam or EKG finding.
- Delivery at a center without pediatric cardiology availability is likely reasonable.
Commentary from Dr. Jared Hershenson (Greater Washington DC), section editor of Pediatric Cardiology Journal Watch: A fetal echocardiogram is a class I recommendation if a chromosomal abnormality is present. The AHA currently recommends a postnatal echocardiogram in all patients with DS regardless of a normal fetal echocardiogram. With a new emphasis on appropriate use criteria in pediatric echocardiography, this may be a subgroup that could be further evaluated. The primary and secondary goals of this study was to determine if there was any missed complex CHD and any CHD postnatal echocardiograms after a normal fetal echo in DS patients. This was a retrospective evaluation of 120 total patients with suspected DS; 72 had complex CHD with the most common diagnoses AVSD and VSD. 45 patients had a normal fetal echo and also had a postnatal echo performed. Complex CHD was defined as a diagnosis with RACHS >/= 3. PFO and PDA were not included as pathologic CHD diagnoses for the purpose of this study. The gestational age at the time of initial fetal echo was 25 +/- 3.5 weeks. The median age at postnatal echo was 7 days, with 24 patients having an echo within the first week of life. No patients had complex CHD; negative predictive value was 100%. 13 patients had minor CHD consisting mostly of ASDs or VSDs; negative predictive value 71.1%. All of them had a heart murmur or EKG abnormality on evaluation. 1/13 patients died from severe PPHN. 3/13 required intervention (2 caths for PDA closure, 1 primum ASD repair). One other patient has a primum ASD that was still being followed (see table 1).
While fetal echocardiography does not have 100% sensitivity for ruling out CHD, this study adds weight to previous studies that missed complex CHD is very unlikely. At a minimum, in an otherwise uncomplicated pregnancy or in a region with many hospitals that do not have direct access to pediatric cardiology, it would seem quite reasonable to deliver patients with a negative fetal echo and refer them to pediatric cardiology within the first few weeks of life. There is unlikely enough evidence to change the postnatal echo recommendations given that there are many minor CHD diagnoses that need to be followed over time; however, the authors do speculate how AUC may be used in this population when adding other historical and clinical factors and an EKG. Limitations of this study include its small sample size and retrospective design, but this study could easily be replicated with a larger cohort.
Fetal Cardiology Sept 2019
Cooper A, Sisco K, Backes CH, Dutro M, Seabrook R, Santoro SL, Cua CL.
Pediatr Cardiol. 2019 Sep 20. doi: 10.1007/s00246-019-02209-w. [Epub ahead of print]
PMID: 31541264
Select item 31568264
McGovern PE, Lawrence K, Baumgarten H, Rossidis A, Mejaddam A, Licht DJ, Grinspan J, Schupper A, Rychik J, Didier RA, Vossough A, Spray TL, Peranteau WH, Davey MG, Flake AW, Gaynor JW.
Ann Thorac Surg. 2019 Sep 18. pii: S0003-4975(19)31405-5. doi: 10.1016/j.athoracsur.2019.08.021. [Epub ahead of print]
PMID: 31541634
Select item 31532081
Bratt EL, Järvholm S, Ekman-Joelsson BM, Johannsmeyer A, Carlsson SÅ, Mattsson LÅ, Mellander M.
Cardiol Young. 2019 Sep 16:1-7. doi: 10.1017/S1047951119001781. [Epub ahead of print]
PMID: 31522698
Select item 31529177
Whitcomb J, Gharibeh L, Nemer M.
IUBMB Life. 2019 Sep 13. doi: 10.1002/iub.2163. [Epub ahead of print] Review.
PMID: 31520462
Select item 31526640
Lange S, Banerjee I, Carrion K, Serrano R, Habich L, Kameny R, Lengenfelder L, Dalton N, Meili R, Börgeson E, Peterson K, Ricci M, Lincoln J, Ghassemian M, Fineman J, Del Álamo JC, Nigam V.
JCI Insight. 2019 Sep 12;4(19). pii: 125507. doi: 10.1172/jci.insight.125507.
PMID: 31513548 Free Article
Select item 28613785
Cawyer CR, Kuper SG, Ausbeck E, Sinkey RG, Owen J.
Prenat Diagn. 2019 Sep 9. doi: 10.1002/pd.5557. [Epub ahead of print]
PMID: 31499581
Select item 31494945
Wang Y, Zhang J, Feng W, Wu Y, Yang L, Yin J.
Echocardiography. 2019 Sep 5. doi: 10.1111/echo.14470. [Epub ahead of print]
PMID: 31487058
Select item 31488903
Graupner O, Helfrich F, Ostermayer E, Lobmaier SM, Ortiz JU, Ewert P, Wacker-Gussmann A, Haller B, Axt-Fliedner R, Enzensberger C, Abel K, Karge A, Oberhoffer R, Kuschel B.
Arch Gynecol Obstet. 2019 Sep;300(3):601-613. doi: 10.1007/s00404-019-05198-6. Epub 2019 May 28.
PMID: 31139902
Select item 31423303
Jarrell DK, Lennon ML, Jacot JG.
Diseases. 2019 Sep 1;7(3). pii: E52. doi: 10.3390/diseases7030052. Review.
PMID: 31480510 Free Article
Select item 31226628
Lytzen R, Vejlstrup N, Bjerre J, Petersen OB, Leenskjold S, Dodd JK, Jørgensen FS, Søndergaard L.
Int J Cardiol. 2019 Sep 1;290:93-99. doi: 10.1016/j.ijcard.2019.05.017. Epub 2019 May 7.
PMID: 31130278
Select item 31085083
- Obstetric and perinatal outcomes in pregnancies with isolated foetal congenital heart abnormalities.
Liu C, Lodge J, Flatley C, Gooi A, Ward C, Eagleson K, Kumar S.
J Matern Fetal Neonatal Med. 2019 Sep;32(18):2985-2992. doi: 10.1080/14767058.2018.1453799. Epub 2018 Apr 3.
PMID: 29544375
Select item 31074499
van Amerom JFP, Lloyd DFA, Deprez M, Price AN, Malik SJ, Pushparajah K, van Poppel MPM, Rutherford MA, Razavi R, Hajnal JV.
Magn Reson Med. 2019 Sep;82(3):1055-1072. doi: 10.1002/mrm.27798. Epub 2019 May 12.
PMID: 31081250 Free PMC Article
Select item 31378336
Ishido H, Baba K, Maeda S, Doi H, Iwamoto Y, Senzaki H, Masutani S.
J Echocardiogr. 2019 Sep 7. doi: 10.1007/s12574-019-00441-0. [Epub ahead of print] No abstract available.
PMID: 31494840
Select item 31494702
Malakan Rad E, Sheykhian T, Zeinaloo AA.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):220-227. doi: 10.4103/apc.APC_146_18.
PMID: 31516278 Free PMC Article
Select item 31516277
Graupner O, Helfrich F, Ostermayer E, Lobmaier SM, Ortiz JU, Ewert P, Wacker-Gussmann A, Haller B, Axt-Fliedner R, Enzensberger C, Abel K, Karge A, Oberhoffer R, Kuschel B.
Arch Gynecol Obstet. 2019 Sep;300(3):601-613. doi: 10.1007/s00404-019-05198-6. Epub 2019 May 28.
PMID: 31139902
Select item 31519455
Rakha S, El Marsafawy H.
Arch Pediatr. 2019 Sep;26(6):337-341. doi: 10.1016/j.arcped.2019.08.001. Epub 2019 Sep 10.
PMID: 31519455
Select item 30234505
May LJ, Lorts A, VanderPluym C, Conway J, Massicotte MP, Millar MM, Steiner ME, Rosenthal DN.
ASAIO J. 2019 Sep/Oct;65(7):731-737. doi: 10.1097/MAT.0000000000000878.
PMID: 30234505
Select item 30161035
Svirsky R, Brabbing-Goldstein D, Rozovski U, Kapusta L, Reches A, Yaron Y.
J Matern Fetal Neonatal Med. 2019 Sep;32(17):2837-2841. doi: 10.1080/14767058.2018.1449829. Epub 2018 Mar 20.
PMID: 29510647
Select item 31169657
Ishido H, Masutani S, Mikami Y, Baba K, Fuse M, Mizuta K, Tanaka R, Sugamoto K, Iwamoto Y, Senzaki H.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):336-338. doi: 10.4103/apc.APC_112_18.
PMID: 31516298 Free PMC Article
Select item 31516297
Rocha LA, Bravo-Valenzuela NJ, Rolo LC, Araujo Júnior E.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):233-239. doi: 10.4103/apc.APC_173_18. Review.
PMID: 31516280 Free PMC Article
Select item 31516279
Malakan Rad E, Sheykhian T, Zeinaloo AA.
Ann Pediatr Cardiol. 2019 Sep-Dec;12(3):220-227. doi: 10.4103/apc.APC_146_18.
PMID: 31516278 Free PMC Article
Select item 31516277
Congenital Cardiovascular Anesthesia and Critical Care Featured Articles
CHD anesthesia and intensive care August 2019
CHD Anesthesia Sept 2019
Steen EH, Lasa JJ, Nguyen TC, Keswani SG, Checchia PA, Anders MM.
J Surg Res. 2019 Sep;241:149-159. doi: 10.1016/j.jss.2019.03.052. Epub 2019 Apr 23.
PMID: 31026793
Select item 31277816
Michel J, Hofbeck M, Peper AK, Kumpf M, Neunhoeffer F.
Curr Med Res Opin. 2019 Sep 17:1-6. doi: 10.1080/03007995.2019.1663689. [Epub ahead of print]
PMID: 31526142
Select item 31529991
Ganigara M, Doshi A, Naimi I, Mahadevaiah GP, Buddhe S, Chikkabyrappa SM.
Semin Cardiothorac Vasc Anesth. 2019 Sep 19:1089253219873004. doi: 10.1177/1089253219873004. [Epub ahead of print]
PMID: 31535945
Select item 31541634
Zaleski KL, Kussman BD.
J Cardiothorac Vasc Anesth. 2019 Sep 3. pii: S1053-0770(19)30915-2. doi: 10.1053/j.jvca.2019.08.048. [Epub ahead of print] Review.
PMID: 31582201
Select item 31446821
Braver O, Semyonov M, Reina Y, Konstantino Y, Haim M, Winter J.
J Cardiothorac Vasc Anesth. 2019 Sep;33(9):2513-2516. doi: 10.1053/j.jvca.2019.04.024. Epub 2019 Apr 26. No abstract available.
PMID: 31130315
Select item 31072707
The CHIP Network Journal Watch Team
Konstantin Averin, MD, MS is an Associate Professor of Pediatrics at the University of Alberta and an Interventional Pediatric Cardiologist at the Stollery Children’s Hospital in Edmonton, Alberta. He received his medical degree from the Feinberg School of Medicine at Northwestern University in Chicago, IL. After medical school, he completed pediatrics residency, pediatric cardiology fellowship and sub-specialty training in pediatric and adult interventional cardiology at the Cincinnati Children’s Hospital in Cincinnati, OH. His clinical and research interests are focused on the percutaneous treatment of pediatric patients with congenital and acquired heart disease with a focus on patients with single ventricle physiology, transcatheter pulmonary valves, and pulmonary hypertension.

Dr. Leong Ming Chern “MC” is an adult congenital heart disease specialist at the National Heart Institute, Kuala Lumpur, Malaysia. He received his medical training at the University of Malaya and pediatric cardiology training at the National Heart Institute. His area of interest includes treatment of adult patients with congenital heart disease and pulmonary hypertension in congenital heart disease.

Dr. Damien Cullington, MBChB MRCP MD FESC is a consultant adult congenital cardiologist who works at Leeds General Infirmary, UK. In summer 2019, he will move over to the newly commissioned North West ACHD Service based in Liverpool, UK. Damien qualified in 2002 from the University of Liverpool and became a substantive consultant in 2016. Prior to this, he worked throughout the North of England and Yorkshire as a cardiology trainee. Damien was awarded a doctorate in medicine (MD) from the University of Hull in 2013 for his work in heart rate in patients with heart failure. He is a member of the Royal College of Physicians (London), Fellow of the European Society of Cardiology and honorary senior lecturer for the University of Leeds. His ACHD subspecialty clinical interests are heart failure, imaging and palliative care. He is regional organiser for ACHD training at Leeds and clinical governance lead for the Leeds congenital cardiac unit. His research interests and wide and far but particularly epidemiology, chronic heart failure in ACHD patients in all its guises, the systemic RV and the univentricle

Dr. Blanche Cupido is a consultant adult cardiologist working at Groote Schuur Hospital, UCT Private Academic Hospital and the University of Cape Town(UCT), South Africa. She completed her physician training in 2009 and her cardiology subspecialist training in 2013. She recently returned to SA after doing a Fellowship in Adult Congenital Heart Disease in Leeds, United Kingdom under the guidance of Dr Kate English. She has established a dedicated unit for Grown Up Congenital Heart Disease in Cape Town, South Africa. Her aim is to grow ACHD services in Sub-Saharan Africa and embark on GUCH research on the African continent.

Dr. Jeremy L. Herrmann is an Assistant Professor of Surgery in the Division of Thoracic and Cardiovascular Surgery at Indiana University. He specializes in pediatric and adult congenital cardiac surgery, and his clinical interests also include heart transplantation and mechanical circulatory support. His hospital affiliations include Indiana University Health Riley Hospital for Children and Methodist Hospital as well as Peyton Manning Children’s Hospital at St. Vincent Hospital in Indianapolis

Maan Jokhadar is a cardiologist and associate professor of medicine at Emory University in Atlanta, Georgia. He is board certified in internal medicine, cardiovascular disease, advanced heart failure/transplantation, adult congenital heart disease, and echocardiography. He is fellowship director for the Emory Adult Congenital Heart Disease training program and Core Curriculum Director for the Emory general cardiology fellowship program. Dr Jokhadar graduated from the University Damascus School of Medicine in Syria and then went to Mayo Clinic in Rochester, Minnesota for internal medicine residency. He then completed cardiology and subspecialty training at Emory University, where he currently on faculty. Dr. Jokhadar has been the recipient of numerous teaching awards. He is married with 3 children.

Michael Ma, MD is an Assistant Professor in Cardiothoracic Surgery in the Division of Pediatric Cardiac Surgery at Stanford University. He specializes in pediatric and adult congenital cardiac surgery, with an emphasis on neonates, complex biventricular repair, and pulmonary artery reconstruction. His research lab investigates ex and in vivo translational models for complex congenital heart disease, to optimize future surgical and endovascular repair strategies.

Jeremy P. Moore MD MS FHRS is the Director of Clinical Research and faculty in Pediatric Cardiology and Adult Congenital Heart Disease at the University of California, Los Angeles. Dr. Moore received his medical degree from the Medical College of Virginia in 2003. He completed residency and fellowship at UCLA before pursuing his subspecialty training in Pediatric Electrophysiology at Vanderbilt University in 2009. Dr. Moore has been faculty at UCLA since 2010 and has since published numerous research manuscripts dealing with electrophysiologic aspects pertinent to congenital heart disease. Dr. Moore’s primary interest is the study of mechanisms of arrhythmia, and the development of novel electrophysiologic techniques for management of the adult patient with congenital heart disease

Dr. Mehul Patel MD, is a structural and adult congenital heart disease specialist and an interventional cardiologist. Dr. Patel earned his undergraduate and medical education from the Mumbai University, India. After completing his post-graduate training in Internal Medicine and Cardiology, he further trained in interventional cardiology at the Mount Sinai Medical Center, NYC, NY and Adult Congenital Heart Disease at the Texas Children’s Hospital, Texas Heart Institute, Baylor College of Medicine, Houston, TX. Dr. Patel worked as Chief of adult congenital heart disease, Assistant Professor at the Michigan State University, Grand Rapids, MI where he not only expanded the program, performing complex interventions and device implantations but also established the percutaneous pulmonary valve implantation (Melody Valve) Program. Due to his passion for treating structurally abnormal hearts, he did a dedicated year of Structural Heart Disease fellowship at Henry Ford Hospital, Detroit, MI where he worked with pioneers in this field before moving to North Carolina. He is proficient in performing transcatheter aortic valve replacement (TAVR), MitraClip, Watchman device implantation, percutaneous Mitral, Tricuspid and Pulmonary valve replacements along with a variety of interventions on congenital heart disease and pulmonary hypertension. Dr. Patel is ABIM board certified in Internal Medicine, Cardiology, Interventional cardiology and Adult Congenital Heart Disease. Dr. Patel has more than 50 peer reviewed publications and numerous abstracts to his credit. He serves as a Co-Editor-in-Chief for the CHiP Network journal watch. His wife, Khyati is a pediatric cardiac Electrophysiologist and they have a 9-year-old daughter. Dr. Patel is also an artist, likes music, yoga and plays badminton. His clinical areas of expertise and interests are: 1) Transcatheter therapies for Structural and Adult Congenital heart disease. 2) Complex device implantations.

Dr. Timothy Pirolli is an Assistant Professor of Surgery in the Division of Pediatric Cardiothoracic Surgery at University of Texas Southwestern Medical Center. He specializes in pediatric and adult congenital cardiac surgery. His hospital affiliations include Children’s Medical Center in Dallas, Parkland Memorial Hospital, and Clements University Hospital (UTSW).

Dr. Inga Voges, M.D. Consultant in Pediatric Cardiology, Lead Consultant Cardiovascular MRI. I trained in General Pediatrics and Pediatric Cardiology in Rostock (Germany) and Kiel (Germany) from 2002-2010 and did additional training in Adult Congenital Heart Disease (ACHD) in Kiel (Germany) which I finished in 2014. I specialized in Cardiovascular Magnetic Resonance Imaging (CMR) and have a further special interest in cardiomyopathies. Currently, I am working as a consultant pediatric and ACHD cardiologist at the University Hospital Schleswig-Holstein (Kiel, Germany) where I am responsible for the CMR imaging program in pediatric and ACHD patients and contribute to the care of patients with acquired and congenital heart disease. I received my MD from the Medical University Luebeck in 2006 (Germany) and finished my “Habilitation” (PhD equivalent; University Hospital Kiel, Germany) in 2014. Since 2016, I am the secretary of the Association for European Paediatric and Congenital Cardiology Imaging Working Group.

Dr. Gary Webb, M.D. is an Emeritus Professor of Pediatrics and Internal Medicine at the University of Cincinnati College of Medicine and,
from 2009-2016, the Director of the Adult Congenital Heart Program at Cincinnati Children’s Hospital Heart Institute. A graduate of McGill
University in Montréal, he interned at the Royal Victoria Hospital, and then trained in internal medicine and cardiology at the University of Toronto. From 1980-2004, he was co-director and then director of the Toronto Congenital Cardiac Center for Adults at Toronto General Hospital. He is a Fellow of the Royal College of Physicians and Surgeons of Canada in both internal medicine and cardiology. From 2004-2009, he was director of the Philadelphia Adult Congenital Heart Center at the University of Pennsylvania. Since 2016, he has been a consultant to Cincinnati Children’s Hospital, and has been responsible for the ACHD Learning Center, the Cardiology Fellow Testing Center, and the Congenital Heart Professionals International (CHIP) Network. Since 2017, he has resumed seeing patients on a part-time basis at the Toronto Congenital Cardiac Centre for Adults.

Wendy Whiteside, MD Wendy is Assistant Professor of Pediatrics and Associate Director of Interventional Pediatric Cardiology at the University of Michigan Congenital Heart Center, C.S. Mott Children’s Hospital. She obtained her medical degree from Albert Einstein College of Medicine in 2006 then completed pediatric residency at Children’s Hospital Oakland in Oakland, CA in 2009. She received
both her categorical and interventional pediatric cardiology training at the University of Michigan in Ann Arbor, MI. Her clinical and research interests include single ventricle physiology, transcatheter
pulmonary valves, and quality improvement within the cardiac catheterization laboratory.

About the Congenital Heart and Pediatric Cardiac Journal Watch
Congenital heart and pediatric cardiac Journal Watch was designed to make it easier for congenital heart and pediatric cardiac professionals to keep up with the literature in 6 subsections of congenital heart disease abstracts on a monthly basis: pediatric cardiology; congenital heart surgery; congenital heart interventions; congenital/pediatric electrophysiology; fetal cardiology; and adult congenital heart disease.
We encourage your continued support as well as your valuable comments and feedback.
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Sincerely,
Dr. Gary Webb, MD and Dr. Mehul Patel
CHiP Network
Congenital Heart and Pediatic Cardiac Journal Watch Editorial Board

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